西安交通大学教职工及部分大学生胃食管反流病患病状况调查  

An Epidemiologic Study of Gastroesophageal Reflux Disease in Xi'an Jiaotong University

作　　者：徐晖[1] 李四季[1] 董德全[1] 艾文静[1] 李彩凤[1] 姚桂兰[1] 

机构地区：[1]西安交通大学医院内科,陕西西安710049

出　　处：《中国慢性病预防与控制》2007年第5期466-468,共3页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：西安交通大学基金项目(JC002036)

摘　　要：目的了解西安交通大学教职工及部分大学生胃食管反流病(GERD)和反流性食管炎(RE)患病情况,并探讨GERD发生的危险因素。方法2001年1月至2002年7月对西安交通大学教职工及部分大学生1418人进行问卷调查。以反酸、反食、烧心的症状程度和频度的积分(Sc)作为反流指标,Sc≥6分表明存在症状性反流,对Sc≥10分者进行胃镜检查,检出RE患者。采用SPSS10.0统计软件进行卡方检验和Logistic多元回归分析。结果调查结果显示GERD患病率为14.74%,RE患病率为3.24%。男性、年龄≥40岁、超重肥胖、进食过饱、喜食甜酸、油腻、吸烟、饮酒、腹胀、便秘、体位反流、家族史、服药为GERD患病的危险因素。结论GERD为西安交通大学师生的常见病和多发病。应改善生活方式,减少患病率。To explore the prevalent rates of gastroesophageal reflux disease （GERD） and reflux esophagitis （RE） of the population in Xi＇an Jiaotong University in the period from Jan 2001 to July 2002 and to identify the risk factors of GERD. Methods 1 418 people, including teachers, students, administrative personnel and workers aged from 18 to 78 （average age 43） yrs, were chosen in Xi＇ an Jiaotong University to answer the questionnaires of GERD and RE. Symptom scores （Sc） of the intensity and frequency of heartburn, acid reflux and regurgitation were consider as indices of acid reflux and Sc I〉 6 indicate the presence of symptomatic gastroesophageal reflux （the highest Sc=18）. The people, whose scores were greater than 10, were examined with gastroscopy to diagnose the RE patients, and the prevalence rate was calculated. In addition, more than 20 related factors including age, overweight or fatness, high fat food taken, gluttony were analyzed. The monovariate and multivariate analysis were made by chisquare test and logistic regression by using statistic software SPSS 10.0. Results The prevalence rate of GERD and RE was 14.74% and 3.24% respectively. Sex （OR 1.507）, overweight or obesity （OR 1.063）, age （OR 2.486）, gluttony （OR 1.567）, smoking （OR 2.800）, high fat and high-protein food （OR 1.053）, heredity （OR 1.206）, constipation （OR 3.163） had been found to be the most likely risk factors. Conclusions The investigation results showed that GERD was the common and frequent disease in Xi ＇an Jiaotong University. Sex, age, overweight or obesity, gluttony, smoking, high fat and high-protein food, heredity, constipation had been found to be the most likely risk factors. The prevalence of GERD may be reduced by improving living style and body-building. Taking PPI preparations for controlled acid, promoting the movement of the gastroenteric and protecting gastroenteric mucous-membrane have been recommended for patients.The operation should be done when the above mentio

关 键 词：胃食管反流病 反流性食管炎 患病率 LOGISTIC模型 

分 类 号：R571[医药卫生—消化系统]