血清同工铁蛋白RIA测定对AFP阴性肝占位性病变的鉴别诊断  

DIFFERENTIAL DIAGNOSIS OF AFP-NEGATIVE OCCUPYING LESIONS IN LIVER WITH ISOFERRITINS RADIOIMMUNOASSAYS

作　　者：黎乐群[1] 林进令[1] 肖强 沈康年[1] 

机构地区：[1]广西医学院附院外科

出　　处：《广西医学院学报》1990年第4期32-35,共4页

基　　金：中国科学院自然科学基金

摘　　要：46例病理诊断的AFP阴性肝占位性病变病人的血清铁蛋白(SF)和酸性铁蛋白(SAF)放射免疫测定结果。结果表明,在这些病人中,原发性肝癌病人约占一半;SF和SAF的放免测定对AFP阴性肝占位性病变的性质具有一定的鉴别诊断价值、有助于对AFP阴性原发性肝癌(HCC)的诊断。SF和SAF放免测定诊断HCC的敏感性分別为57.1%和76.2%,特异性分別为96.0%和100%,诊断准确性分别为78.3%和89.1%。结果提示,对AFP阴性HCC的诊断价值,SAF优于SF。Serum ferritin(SF)and serum acid ferritin(SAF)were mea- sured in 46 patients with AFP-negative occupying lesions in the liver,using radioimmunoassays of SF and SAF.Our results showed that about half of these cases were patients with hepatocellular carcinoma(HCC).Radioimmunoassays of SF and SAF help to distinguish patients with HCC from patients with other occupying lesions in liver.The sensitivity of diagnosing HCC with radioimmu- noassays of SF and SAF was 57.1% and 76.2% respectively,the specificity was 96.0% and 100% respectively and the diagnostic accuracy was 78.3% and 89.1% respectively.All these results suggested that SAF measurement is more excellent than SF measurement in the diagnosis of AFP-negative HCC.

关 键 词：同工铁蛋白 肝癌 占位性病变 

分 类 号：R735.704[医药卫生—肿瘤]