62例鼻腔NK/T细胞淋巴瘤的临床预后分析  

Analysis of clinicopathological features and prognostic factors of 62 nasal NK/T-cell lymphomas

作　　者：徐刚[1] 王槐富[1] 谢可[2] 何刚[1] 杜泽秀[1] 

机构地区：[1]四川省医学科学院四川省人民医院耳鼻咽喉科,成都610072 [2]四川省人民医院肿瘤科

出　　处：《临床耳鼻咽喉头颈外科杂志》2007年第20期932-934,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨鼻腔NK/T细胞淋巴瘤的临床病理特征及影响预后的因素。方法:分析62例鼻腔NK/T细胞淋巴瘤的临床资料、病理特征、治疗和生存情况。结果:62例患者总的5年生存率为63.5%。单因素分析显示,年龄、穿孔、B症状、分期、Hb浓度、血清乳酸脱氢酶水平、瘤细胞大小、累及部位数量、血管浸润和治疗方式与预后关系密切(P<0.05或P<0.01);多因素分析显示,Hb浓度、瘤细胞大小和治疗方式是该病独立的预后因素(P<0.01或P<0.05)。结论:Hb浓度、瘤细胞大小和治疗方式是鼻腔NK/T细胞淋巴瘤主要的预后因素。Objective：To investigate the clinicopathological features and prognostic factors of nasal NK/T-cell lymphoma. Method：The clinicopathological data, treatment modality and survival status were analyzed. Result： The overall five year survival rate of 62 patients was 63.5%. In univariate analysis, the prognosis of the patients was correlated with the age, perforation,B symptom, stage, Hb concentration, LDH level , size of tumor cell, number of involvement sites, angioinvasion and treatment modality（ P〈0.05 or P〈0.01）. In multivariate analysis, the Hb concentration, the size of the tumor cell and the treatment modality were the independent prognostic factors. Conclusion：The Hb concentration, the size of the tumor cell and the treatment modality play key role in the prognosis of nasal NK/T-cell lymphoma.

关 键 词：鼻肿瘤 淋巴瘤 NK/T细胞 预后 

分 类 号：R733.4[医药卫生—肿瘤]