Amberlyst 15催化下合成双亚苄基环烷酮类化合物  

Synthesis of α,α′-Bisbenzylidenecycloalkanones Catalyzed by Amberlyst 15

作　　者：康丽琴[1] 魏邦国[2] 

机构地区：[1]上海应用技术学院,上海200235 [2]中国科学院上海有机化学研究所,上海200032

出　　处：《化学通报》2007年第10期801-804,共4页Chemistry

摘　　要：以乙醇为溶剂,在70℃下用强酸性阳离子交换树脂Amberlyst15催化芳香醛与环己酮缩二乙醇或环戊酮缩二乙醇反应2～6h后,以产率80%～92%得到α,α′-双亚苄基环烷酮类化合物。产物结构经熔点,IR和1HNMR确证。产物后处理简单,没有醛或缩酮的自缩合产物生成,是一种环境友好的绿色合成方法。Abstract A series of α,α′-bis（substituted benzylidene）cycloalkanones were synthesized by condensation reaction of aromatic aldehydes with cyclohexanone ketal or cyclopentanone ketal using strong- acid cation exchange resin Amberlyst 15 as catalyst in ethanol media. The reactions were completed during 2 - 6 h with 80% ～ 92% yields. The structure of the products was characterized by IR, ^1H NMR, MS and the melting point. The products were convenient to work up. This process is simple, efficient, environmentally benign and without anv self-condensation.

关 键 词：AMBERLYST 15 芳香醛 缩酮 催化剂 

分 类 号：O624[理学—有机化学] O643.32[理学—化学]