手性分子识别中空纤维复合膜制备及其性能的研究  

Study on the Preparation of Dibenzoyl-L-tartaric Acid(L-DBTA) Imprinted Composite Membranes and its Properties

作　　者：杨座国[1] 顾小炎 许振良[1] 惠绍梁 邴乃慈[1] 

机构地区：[1]华东理工大学化学工程研究所,上海200237 [2]上海化学试剂研究所,上海200241

出　　处：《高校化学工程学报》2007年第5期760-765,共6页Journal of Chemical Engineering of Chinese Universities

基　　金：国家重点基础研究发展计划(973计划)(2003CB615705);上海华谊(集团)公司-华东理工大学先进化学与化工技术研究中心资助

摘　　要：以聚砜(PSF)中空纤维超滤膜为基膜,采用表面热聚合方法制备了L-DBTA印迹中空纤维复合膜。由SEM分析表明经过表面聚合后的L-DBTA印迹中空纤维复合膜表面具有层叠交联状复合层,其厚度约3μm。复合层表面与层内具有许多"空穴",其直径在200nm以下。实验结果表明L-DBTA印迹中空纤维复合膜对模板分子L-DBTA具有很好的识别作用,对L,D-DBTA的分离因子α可达2.7,而非分子印迹复合膜对L-DBTA的识别选择性不明显。此外,当引发剂的浓度为4.0%,60℃表面热聚合48h制得的L-DBTA印迹中空纤维复合膜对L-DBTA具有较好的识别性能,具有良好的应用前景。Using polysulfone （PSF） hollow fiber membrane as the supported membrane, the chiral （L-DBTA） molecular imprinted hollow fiber composite membrane （CMn-IFCM） was prepared by surface thermal-polymerization method and the recognition properties of prepared CMIHFCM for enantioseparation was studied. After surface polymerization, the external surface of CMIHFCM prepared has a complex network layer with the thickness of 3μm which is thicker than that of the original supported membrane, and in the complex network layer, there are many ＂caves＂ with sizes less than 200nm. The experimental results show that, using the prepared CMIHFCM, the L-DBTA solution can be condensed greatly and the separation factor （α） of L-DBTA and D-DBTA could reach 2,7, It indicates that the prepared CMIHFCM has a good recognition ability for the template L-DBTA, while for the non-molecularly imprinted membrane, its recognition towards L-DBTA is not so obvious, It was found that when the concentration of initiator used is 4.0% and after surface thermal polymerization at 60℃ for 48 hours, the CMIHFCM with good recognition property towards L-DBTA can be prepared.

关 键 词：分子印迹 复合膜 手性识别 二苯甲酰-L-酒石酸 

分 类 号：TQ028.8[化学工程]