血清总胆汁酸的表达与婴幼儿肝炎综合征  

Signification of Serum Total Bile Acid Determination in Infantile Hepatitis Syndrome

作　　者：梅德生 

机构地区：[1]光山县人民医院检验科,河南光山465450

出　　处：《河南职工医学院学报》2007年第6期525-526,共2页Journal of Henan Medical College For Staff and Workers

摘　　要：目的探讨血清总胆汁酸(TBA)在婴幼儿肝炎综合征中的表达。方法采用全自动生化分析仪测定63例肝炎综合征患儿与对照组30例非肝胆疾病患儿TBA的表达水平,后进行比较。结果对照组的TBA表达明显低于患儿组的TBA,两组比较差异有统计学意义P<0.01),而与谷丙转氨酶(GPT)总胆红素(TBIL)有一定相关性(P<0.01),且TBA的阳性率高于谷丙转氨酶(GPT)的阳性率(P<0.05)。结论血清TBA的表达在反映肝功能损伤方面是一个灵敏的指标,对婴幼儿肝炎综合征患儿的早期诊断治疗和预后有重要临床意义。Objective To investigate the clinical significance of measuring serum TBA in liver and gallbladder diseases. Methods Serum TBA and other liver function related items were determined with automic enzymatic assay techniques in 63 with infantile hepatitis syndrome patients （21 days -7years） and 30 normal infants （20 days -7years）. Results In 95% patients the serum TBA level was abnormal and the average values were 65.1 ± 10.5 umol . L^ -1 ,in the control group the serum TBA level was 9.4 ± 4.6 the TBA level were well related to those of GPT TBIL DBil and TBA was better than others in sensitivity and specificity. Conclusion Serum TBA level is important in evaluating the diagnosis,treatment, and prognosis of infantile hepatitis syndrome.

关 键 词：总胆汁酸 婴幼儿肝炎综合征 

分 类 号：R575.1[医药卫生—消化系统]