牙周炎与冠心病关系的META分析  

Meta Analyses on the Correlation between Chronic Periodontitis and Coronary Heart Disease

作　　者：王承明[1] 张玲[2] 

机构地区：[1]荆楚理工学院继续教育学院,湖北荆门448000 [2]武汉科技大学医学院,湖北武汉430000

出　　处：《荆门职业技术学院学报》2007年第9期57-61,共5页Journal of Jingmen Technical College

摘　　要：目的：应用META分析技术定量评价慢性牙周炎与冠心病的联系。方法：检索中国期刊网、维普、万方数据等医学数据库，手工检索相关杂志并追查参考文献。独立筛选、评价文献和提取数据。对数据进行异质性检验后，借助Revman4．2分析软件并根据其文献来源是否为同质总体而选择不同的Meta分析。结果：纳入6篇文献（794例病例）。冠心病纽慢性牙周炎患病率为50．5％，而对照纽仅为32．6％，两者差异有统计学意义（P〈0．001）。单因素分析，慢性牙周炎与冠心病密切相关（OR=2．34，95％CI：1．16-4．73）。慢性牙周炎和冠心病不仅有统计学上的关联，还具有明显的剂量反应关系。结论：慢性牙周炎可能是冠心病的独立危险因素。Objective：To explore the correlation between chronic periodontitis （CP） and coronary heart disease （CHD）. Methods： Three medical databases were searched, including CNNC, WEIPU and WANFANG, together with hand - searched, and references of included studies additionally searched. Reviewed the original articles, evaluating qualities of articles, and extracting data independently. After heterogeneity test, the data was pooled using Revman software if capable ,or descriptive analysis was applied. Results： In total,6 original clinical controlled trials were included, containing 794 cases. Chronic periodontitis illness rate is the group of coronary heart disease 50.5 % ,and comparing with group is only 32.6 % ,two discrepancies have statistics meaning （ P 〈 0. 001 ）. Single factor is analysed, chronic periodontitis and coronary heart disease are related closely （ OR =2.34,95% CI：1. 16-4.73）. Chronic periodontitis and coronary heart disease not only have the relation on statistics, and have obvious dosage reaction relation. Conclusion：Chronic periodontitis is the independently dangerous factor of coronary heart disease probably.

关 键 词：慢性牙周炎 冠心病 危险因素 META分析 

分 类 号：R781.42[医药卫生—口腔医学]