肝气郁结证患者脑电非线性分析参数点关联维数的研究  

Study on Point-wise Correlation Dimension of Electroencephalogram Nonlinear Analysis in Patients with Stagnation of Liver-Qi Syndrome

作　　者：刘子旺[1] 王玉来[2] 尹岭[3] 姚斌[3] 郭蓉娟[2] 赵永烈[2] 滕晶[4] 秦绍林[2] 王爱成[1] 

机构地区：[1]北京中医药大学第三附属医院急诊科,北京市100029 [2]北京中医药大学东方医院,北京市100078 [3]解放军总医院神经信息中心,北京市100853 [4]山东中医药大学附属医院,山东济南市250011

出　　处：《中国康复理论与实践》2007年第10期960-962,F0003,共4页Chinese Journal of Rehabilitation Theory and Practice

基　　金：国家自然科学基金(No.30472213);北京市自然科学基金(No.7042029)

摘　　要：目的探讨肝气郁结证患者脑电非线性动力学变化规律。方法15例肝气郁结症患者和15例正常受试者按年龄、性别配对,用参数PD2对安静闭眼、安静睁眼、睁眼心算3种状态下的脑电数据进行分析。结果3种状态下肝气郁结证患者大脑皮质的PD2较正常人增高,一直维持在较高水平,并随刺激条件的增多,两者之间PD2的差异逐渐缩小。结论脑电非线性分析能相对客观和准确地观测到肝气郁结证患者大脑皮质的变化,可用于肝气郁结证脑机制的研究。Objective To investigate the changes of non-linear with the stagnation of Liver-Qi syndrome. Methods 15 Liver-Qi dynamics characteristics ot electroencephalogram （EEG in patients stagnation syndrome patients and 15 normal persons were paired by sex and age. The data of EEG under three states （eyes closed, eyes opened, and mental arithmetic with eyes opened） were analyzed by the parameter of point-wise correlation dimension （PD2）. Results PD2 of the stagnation of Liver-Qi syndrome group increased significantly compared with that of the healthy control group and always maintain high level. The difference of PD2 between two groups was gradually reduced along with the increase of stimulated condition. Conclusion Non-linear dynamic analysis is more appropriate for the study of mental functions changes of stagnation of Liver-Qi syndrome and can be used to investigate the brain mechanism of the stagnation of Liver-Qi syndrome.

关 键 词：肝气郁结证 脑电图 非线性动力学 点关联维数 

分 类 号：R741.044[医药卫生—神经病学与精神病学]