放射治疗骨转移癌加艾本的临床观察  

Analysis of the therapeutic effect of ibandronate and radiotherapy on 96 cases of bone metastases

作　　者：陈林[1] 王林海[1] 栾瑾微[1] 郭汝涛[1] 

机构地区：[1]哈尔滨医科大学第三临床医学院放射治疗科,黑龙江哈尔滨150081

出　　处：《哈尔滨医科大学学报》2007年第5期489-490,493,共3页Journal of Harbin Medical University

摘　　要：目的观察放射治疗及艾本对骨转移癌的止痛效果。方法对96例骨转移癌患者进行回顾性分析,单纯放射治疗30例,艾本加放射治疗14例,艾本加放化疗56例。结果全组总有效率89%,显效率51%。各组有效率:单放组为83.3%,艾本加放射治疗组为92.9%,艾本加放化疗组94.2%。三组间止痛效果无显著性差异(P>0.05)。在应用艾本治疗组中有1例出现类似过敏反应症状,其他无明显毒副作用反应发生。结论放射治疗骨转移癌止痛迅速而有效。艾本治疗骨转移癌止痛效果明显,尤其适合应用于多发性骨转移癌患者,二者联合应用效果更加明显。Objective To evaluate the therapeutic effects of radiotherapy and ibandronate on bone metastases. Methods Ninety-six cases were analyzed retrospectively. Thirty cases were included in radiation therapy group, 14 cases in ibandronate combination with local radiotherapy group and 56 cases in ibandronate combination with chemo-radiotherapy group. Results The overall effective rate of ibandronate for bone pain relieving in the 96 patients with bone metastases was 89%, the complete response rate was 51%. The response rates of radiotherapy group, ibandronate combination with radiotherapy group and ibandronate combination with chemoradiotherapy group were 83.3%, 92.9% and 94.2%, respectively. Conclusion Radiotherapy and ibandronate are effective methods on bone metastases. Ibandronate combination with radiotherapy is more effective on bone metastases patients.

关 键 词：骨转移癌 放射治疗 艾本 

分 类 号：R730.5[医药卫生—肿瘤]