上呼吸道黏膜相关性淋巴组织淋巴瘤临床及病理特征分析  

Analysis on the clinical and pathologic characteristics of mucosa associated lymphoid tissue lymphoma in upper respiratory tract

作　　者：易彦[1] 葛圣雷[2] 

机构地区：[1]中南大学湘雅二医院血液科,湖南长沙410011 [2]中南大学湘雅二医院耳鼻咽喉科,湖南长沙410011

出　　处：《中国医师杂志》2007年第10期1303-1304,共2页Journal of Chinese Physician

基　　金：湖南省自然科学基金资助项目（06CD034）

摘　　要：目的提高对上呼吸道黏膜相关性淋巴组织（MALT）淋巴瘤的临床及病理特征认识。方法收集本院确诊的上呼吸道MALT淋巴瘤6例,对其临床特点及病理特征进行回顾性分析研究。结果6例患者中,男5例,女1例;原发鼻腔者4例,咽1例,喉1例;单用手术治疗4例,手术加放疗1例,手术加放、化疗1例;随诊6个月至3年,5例病情稳定,1例远处转移。6例患者均具有MALT淋巴瘤的特征性病理改变。结论原发于上呼吸道的MALT淋巴瘤与原发于其它部位的MALT淋巴瘤一样,好发于男性,进展慢,B症状少见,治疗效果和预后良好。Objective To better understand the clinical and pathologic characteristics of mucosa associated lymphoid tissue （MALT） lymphoma in upper respiratory tract. Methods The clinical, histological and immunohistochemistric manifestations in six MALT lymphoma patients primarily arising in upper respiratory tract were studied. Results In six patients, 4 patients had primary involvement of nose, 1 patient of pharynx and 1 patient of larynx. Among the 6 cases, surgical resection was performed alone in 4 cases, with adjuvant radiotherapy in 1 case and with radiotherapy and chemotherapy in 1 case. At the end of our follow - up of six months to three years, five of them were disease free, one appeared of metastasis. Conclusion MALT lymphoma in upper respiratory tract have no associated adverse prognostic factors and MALT lymphoma patients have a high response rate to treatment and a long survival.

关 键 词：淋巴瘤 黏膜相关淋巴样组织 呼吸道黏膜 

分 类 号：R733[医药卫生—肿瘤]