不同年龄抑郁症患者瞬目反射的研究  

The study of blink reflex in patients of different ages with major depression

作　　者：张承洁[1] 袁勇贵[1] 梅刚[1] 

机构地区：[1]南京医科大学附属脑科医院,江苏南京210029

出　　处：《临床神经电生理学杂志》2007年第5期290-292,共3页Journal of Clinical Electroneurophysiology

基　　金：南京市医学科技发展项目资金资助(YKK0351)

摘　　要：目的:探讨抑郁症与瞬目反射(BR)的关系。方法:对90例抑郁症(青年和老年各45例)患者及60例正常对照组(青年和老年各30例)进行BR检测。结果:与青年对照组和老年对照组比较,青年抑郁症患者和老年抑郁症患者BR的R2、R2′潜伏期分别显著延长(P<0.001),老年抑郁症患者的波幅与老年对照组、青年抑郁症患者的波幅相比显著升高,差异存在极显著意义(P<0.001)。结论:抑郁症患者存在BR的异常,提示抑郁症患者可能存在脑干功能障碍。Objective：To evaluate the relationship between major depression and blink reflex（BR）. Methods： Blink reflex were measured in 90 patients with major depression and 60 healthy volunteers. Results： The latency of R2 and R2′were significantly lengthened in young depression（YD） and older depression（OD） than those in young eontrols（YC） and old eontrols（OC） respeetively（P〈0. 001） ; The amplitude of R2 and R2′ in the patients with major depression was statistically higher than those Of YD and OD respectively（P〈0. 001）. Conclusions： There is abnormity of blink reflex in the patients with major depression, and it should be denoted that there is functionary disorder in the brain stem in old patients with depression.

关 键 词：抑郁症 青年 老年 瞬目反射 

分 类 号：R749.4[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]