PTCD联合氩氦刀治疗不能切除的原发性肝癌  

Ar-He targeted cryoablation combined with PTCD in the treatment of obstructive liver cancer

作　　者：宋华志[1] 于洪波[2] 易锋涛[1] 谢雄亮[1] 

机构地区：[1]广州军区武汉总医院肿瘤微创治疗中心,430070 [2]南方医科大学珠江医院普外科

出　　处：《腹部外科》2007年第5期271-272,共2页Journal of Abdominal Surgery

摘　　要：目的探讨PTCD联合氩氦刀治疗不能切除的原发性肝癌的临床效果。方法对我院2003年2月～2004年12月收治的15例梗阻型肝癌先作PTCD解除黄疸,保护肝、肾功能。然后,用氩氦刀靶向消融治疗肿瘤。术后定期随访观察肝、肾功能及肿瘤大小的变化。结果本组无手术死亡病例。术后生存期大于1年者5例,8个月6例,半年3例。术后2个月死于肝、肾功能衰竭1例。术后肿瘤直径缩小1～4.2cm,平均为2.8cm。总胆红素和直接胆红素降至正常12例,胆管扩张消失10例。未发生与治疗相关的严重并发症。结论氩氦靶向消融联合PTCD,标本兼治,效果肯定,术后并发症少,是提高梗阻型肝癌治疗效果的有效手段。To investigate the clinical effects of targeted cryoablation combined with percutaneous transhepatic cholangial drainage（PTCD）in the treatment of obstructive hepatocelluar carcinoma. Methods Fifteen patients with obstructive hepatocellular carcinoma were subjected to PTCD to free jaundice and protect hepatic and renal function, then to the treatment of targeted cryoablation. The hepatic and renal function and changes of tumor size were periodically observed. Results Five cases have survived for over 1 year,6 cases for 8 months,and 3 cases 6 months. One case was died from hepatic and renal function failure 2 months postoperation. The size of tumor was decreased by 1～4. 2em in diameter（average 2.8cm）. T-Bil and l〉Bil in 12 cases were reduced to normal,and biliary dilation in 10 cases disappeared. There were serious complications related with operation. Conclusion The treatment of targeted cryoablation combined with PTCD is an effective method for improving the therapeutic effects of obstructive liver carcinoma.

关 键 词：综合疗法 肝肿瘤 胆汁郁积 

分 类 号：R735.7[医药卫生—肿瘤]