吉安县农村50岁以上人群原发性闭角型青光眼流行病学调查  

Epidemiological survey of primary angle-closure glaucoma in rural population aged 50 and elderly

作　　者：白永泉[1] 易敬林[1] 谢晖[1] 罗荣[1] 杨海军[1] 李岚[1] 赖平红[1] 黄倞[1] 杜红岩[1] 

机构地区：[1]江西省人民医院眼科,南昌330006

出　　处：《医学信息（手术学分册）》2007年第9期774-777,共4页Medical Information Operations Sciences Fascicule

摘　　要：目的调查50岁以上的中老年人群的原发性闭角型青光眼患病率并讨论其相关影响因素。方法于2006年11～12月在江西省吉安县以自然村为单位,通过重组随机整群抽样确定50岁以上人群为检查对象,对5013人进行青光眼筛查。采用Van Herick法检测周边前房深度,常规检测视力、屈光状态,直接眼底镜检查视乳头C/D大小,询问病史和家族史,对可疑青光眼和青光眼患者进行青光眼标准检查,其中包括便携式Goldmann压平式眼压检查、Glodmann房角镜前房角检查、视野检查、HRTⅡ、SL-OCT等检查。结果本次调查50岁以上农村特定人群的应答率93.1%(5031/5402),人群中PACG患病率1.5%(76/5013),95%可信区间(CI)0.9%～2.0%,男性和女性患病率分别为1.0%(95%CI0.6%～1.2%)、1.9%(95%CI1.4%～2.1%),在50～59、60～69和70～87岁年龄组中分别为0.5%、2.3%和2.4%。60岁以上年龄段为患病率骤升年龄段,前房角<20°者中有40.6%(76/187)为原发性闭角型青光眼,HRTⅡ对原发性闭角型青光眼的检出率为89.5%(68/76)。回归校正混杂作用后,PACG患病率与前房角解剖、性别、年龄相关。结论原发性闭角型青光眼是重要致盲性眼病,年龄、性别和前房角度数大小为其发病的高危因素。Objective To investigate the prevalence of primary angle -closure glaucoma（PACG） in elderly popu-ation（ aged 50 and elderly）, A quantitative comparison was made based on the data collected from this epidemiological survey. Methods The subjects were identified by clustering samplings scheme in Ji An County, from November to December 2006. There were 5013 subjects in all. The peripheral depth of the anterior chamber was estimated by Van Herick technique. Visual acuities, including naked eye, refracted acuity, were measured by ETDRS visual chart. C/D ratio assessment by direct electric ophthalmoscopy was also carried out. The onset history and family history were inquired. Subjects regarded as suspected glaucoma and glaucoma patients were reexamined with standard glaucomatous examination. There were intraocular pressure measurement by Goldmann tonometer, the examination of the anterior chamber by Goldmann gonioscopy, visual field texts, Heidelberg Retina Tomograph Ⅱ （ HRT Ⅱ ） examination and inferior ocular SL - OCT. Results The response rate of rural population aged 50 and elder was 93.1%. The prevalence of PACG was 1.5% （95% CI 0.9% -2.0% ）. The prevalence of PACG in female was more than in male, 1.9% （95% CI 1.4% - 2. 1% ）vs. 1.0% （95%CI 0.6% - 1.2% ）. Prevalence was0.5% ,2.3% and 2.4% in the 50 -59,60 -69 and 70 - 87 years old group respectively. A drastic increase in prevalence of PACG with age increase was aged 60 - 69 years old group. The percent of PACG was 40.6% （76/187） in the population of the peripheral anterior chamber under 20° in all. The positive of PACG examined was 89.5% （68/76） by HRT Ⅱ. After adjusting the confounding effects with logistic regressing model,the prevalence of PACG was related to anterior chamber angle, age and gender. Conclusions PACG remains as the main cause of blindness in elderly population. Elderly people with shallow anterior chamber and gender are significant risk population.

关 键 词：青光眼 闭角型 患病率 流行病学 

分 类 号：R775.2[医药卫生—眼科]