癌症患者生命质量测定量表体系之肺癌量表QLICP-LU的研制与测量学特性评价  

Development and Psychometric Properties of the System of Quality of Life Instruments for Cancer Patients:Lung Cancer QLICP-LU

作　　者：万崇华[1] 张灿珍[2] 李高峰[2] 沈丽达[2] 罗家洪[1] 杨铮[1] 孟琼[1] 

机构地区：[1]昆明医学院公共卫生学院,云南昆明650031 [2]云南省肿瘤医院,云南昆明650031

出　　处：《中国肿瘤》2007年第11期858-861,共4页China Cancer

基　　金：云南省自然科学基金(99C0016G)

摘　　要：[目的]研制肺癌患者生命质量测定量表QLICP-LU并对其测量学特性进行评价。[方法]采用程序化决策方式(议题小组和核心小组)和量表开发理论分别研制共性模块与特异模块,二者结合形成量表,并通过85例肺癌患者进行的生命质量测定对量表的测量学特性(信度、效度、反应度)进行评价。所用到的统计学方法有相关分析、因子分析及配对t检验等。[结果]该量表的重测信度为0.78,各领域内部一致性α值及重测信度值大多在0.7以上;相关分析与因子分析显示较好的结构效度;与FACT-L为效标的效标关联效度为0.82;治疗后各领域及总量表得分均有统计学意义,且标准化反应均数SRM除社会功能外均大于0.8。[结论]QLICP-LU具有较好的信度、效度及反应度,可用于中国肺癌患者的生命质量测定。[Purpose] To develop and evaluate the psychometric properties of the quality of life instrument QLICP-LU for patients with lung cancer. [Methods ] The structured group methods （nomi- nal group and focus group） and the theory in developing rating scale were employed to establish the general and specific modules, respectively. The full instrument was formed by combination of two modules and psychometric properties （reliability, validity, responsiveness） were evaluated by QOL data measured from 85 in-patients with lung cancer. Statistical methods were correlation analysis, factor analysis and paired t test etc. [Results ] Test-retest reliability of the overall scale was 0.78, and test-retest reliability and internal consistency αfor most domains were higher than 0.70; Correlation and factor analysis demonstrated good structure validity; Criterion-related validity was 0.82 given FACT-L as the criterion; Statistically significant change was found in each domain and the overall scale with standardized response mean SRM being greater than 0.80 except of social function domain. [Conclusionl The QLICP-LU can be used to measure QOL for patients with lung cancer with better validity, reliability and responsiveness.

关 键 词：肺肿瘤 生命质量 量表 测量学特性 

分 类 号：R730.1[医药卫生—肿瘤] R734.2[医药卫生—临床医学]