In vitro Acute Cytotoxicity of Abamectin to the Gill Cell Line of Flounder Paralichthy olivaceus  

作　　者：XU Yuyan GUO Huarong XIAO Qin SU Feng YIN Licheng 

机构地区：[1]College of Life Science and Technology, Ocean University of China, Qingdao 266003, P. R. China

出　　处：《Journal of Ocean University of China》2007年第4期369-372,共4页中国海洋大学学报（英文版）

摘　　要：The cytotoxicity of abamectin to the Gill Cell Line of Flounder （FG cell line） was examined in this study. It was found that the exposure of FG cells to abamectin caused the decreases of both cell growth rate and antioxidant enzyme activities, and the increase of intracellular 02 content. It was proposed that the reduction of antioxidant enzyme activities in FG cells caused the accumulation of 02 content in FG cells, leading to the change of cell morphology and even the death of cells. The results showed that FG cell line is suitable for the evaluation of the acute toxicity of abamectin.The cytotoxicity of abamectin to the Gill Cell Line of Flounder (FG cell line) was examined in this study. It was found that the exposure of FG cells to abamectin caused the decreases of both cell growth rate and antioxidant enzyme activities,and the increase of intracellular O2- content. It was proposed that the reduction of antioxidant enzyme activities in FG cells caused the accu- mulation of O2- content in FG cells, leading to the change of cell morphology and even the death of cells. The results showed that FG cell line is suitable for the evaluation of the acute toxicity of abamectin.

关 键 词：ABAMECTIN antioxidant enzymes cell line CYTOTOXICITY 

分 类 号：Q5[生物学—生物化学]