味觉电生理建模和仿真的研究进展  

Development of taste electrophysiological model and simulation

作　　者：陈培华[1] 王平[1] 

机构地区：[1]浙江大学生物传感器国家专业实验室生物医学工程教育部重点实验室生物医学工程与仪器科学学院,杭州310027

出　　处：《国际生物医学工程杂志》2007年第5期278-282,共5页International Journal of Biomedical Engineering

摘　　要：味质的结构和化学多样性决定了味觉有基于不同味觉物质的多种传导机制。近年来，随着分子生物学、细胞电生理研究方法的发展，有关味觉受体细胞电生理特性、味觉传导机制及味觉编码的研究取得了很大进展。综述了目前国际上味觉受体细胞电生理特性及其建模仿真方法的研究进展，同时评述目前味觉电生理建模仿真的几种主要方法的特点，最后论述了建模仿真方法对味觉机理以及味觉临床病理学研究的重要意义。The structure and the chemical diversity of the tastant determines the multiple transduction mechanism of taste. With the development of studies on molecular biology and cellular electrophysiology. Great progresses have been made recently in studies of electrophysiological feature of taste receptor cells, taste transduction and taste coding. The developments of study on electrophysiological features of taste receptor cells an.d their different modeling and simulation are reported in this paper. Significances of the modeling and simulation in the studies of taste transduction and clinic pathology are reviewed as well.

关 键 词：味觉 味觉受体细胞 味觉传导 建模仿真 

分 类 号：R3[医药卫生—基础医学]