口腔矫治器治疗阻塞性睡眠呼吸暂停综合征的临床研究  

Clinical research on treatment of obstructive sleep apnea syndrome with improved oral appliance

作　　者：宋冬生[1] 尹林[1] 张希龙[2] 

机构地区：[1]南京医科大学第一附属医院口腔科,南京210029 [2]南京医科大学第一附属医院呼吸科,南京210029

出　　处：《口腔医学》2007年第9期469-470,共2页Stomatology

摘　　要：目的评价改良口腔矫治器治疗阻塞性睡眠呼吸暂停综合征(OSAS)的临床疗效。方法采用下颌前移式口腔矫治器治疗24例OSAS患者,治疗前后分别经夜间多导睡眠监测(PSG),比较睡眠呼吸暂停指数(AI)、呼吸暂停低通气指数(AHI)、最低血氧饱和度(SaO2)等呼吸紊乱指标的变化。结果治疗前、后患者呼吸暂停指数、呼吸暂停低通气指数、血氧饱和度指标变化差异有显著性(P<0.001),21例呼吸暂停低通气指数下降了50%以上,客观有效率为87.5%。结论改良口腔矫治器是治疗轻、中度阻塞性睡眠呼吸暂停综合征的有效方法。Objective To investigate the clinical effects of an oral appliance on obstructive sleep apnea syndrome. Methods 24 patients with OSAS treated with mandibular advancement appliance were re-examined by PSG monitoring equipment at night. The changes of the sleep disorder indexes were analyzed. Results 21 patients responded to the oral appliance therapy, their apnea index and apnea-hyponea index were reduced significantly （P 〈 0. 001 ）and the lowest degree of blood oxygen saturation improved significantly （P 〈 0. 001 ）. Conclusion The results demonstrate the oral appliance is an effective alternative that could benefit mild or moderate patients with OSAS.

关 键 词：口腔矫治器 阻塞性睡眠呼吸暂停综合征 

分 类 号：R783.5[医药卫生—口腔医学]