经内镜胆道金属支架引流术治疗恶性胆道梗阻性黄疸  

Clinical Application of Endoscopic Metal Biliary Endoprosthesis for Treatment of Malignant Biliary Obstruction

作　　者：刘建辉[1] 黄年根[1] 陈彬[1] 王顺金[1] 黄平[1] 李凌[1] 徐华[1] 吴建兵[1] 兰琼玉[1] 

机构地区：[1]南昌大学第二附属医院肿瘤科,南昌330006

出　　处：《实用临床医学（江西）》2007年第9期42-43,45,共3页Practical Clinical Medicine

摘　　要：目的:探讨经内镜胆道金属支架引流术治疗恶性胆道梗阻性黄疸的疗效和安全性。方法:42例无法行手术根治性切除的恶性胆道梗阻性黄疸患者采用内镜下胆道金属支架引流术治疗。并观察血清胆红素水平及术后并发症情况,随访患者生存期和胆道支架维持通畅时间。结果:42例患者放置胆道金属支架均获成功,成功率为100.0%(42/42);术后2周内血清胆红素恢复正常30例(71.4%),明显减退12例(28.6%);2例(4.8%)发生胆管炎,3例(7.1%)发生急性轻型胰腺炎;平均支架维持通畅时间为9.6个月;6个月和1年生存率分别为64.3%(27/42)和19.0%(8/42)。结论:经内镜胆道金属支架引流术治疗恶性胆道梗阻性黄疸疗效较好,并发症少。Objective：To evaluate the effect and safety of endoscopic metal biliary endoprosthesis（EMBE） in management of malignant biliary obstruction.Methods：Forty-two patients with unresectable malignant biliary obstruction were treated with EMBE.The level of serum bilirubin,postoperative complications,survival and the unobstructed time of biliary stents were observed.Results： All 42 patients with metal biliary endoprosthesis were placed successfully.The success rate of EMBE was 100.0%.Serum bilirubin in 30 patients（71.4%） in two weeks after the treatment recuperated normal level;12 cases（28.6%） were significantly decreased.The cholangitis occurred in 2 cases（4.8%）,and the mild acute pancreatitis occurred in 3 cases（7.1%）.The average unobstructed time of biliary stents was 9.6 months.The survival rates of six months and one year were 64.3% and 19.0%,respectively.Conclusion：The study showed that the therapy of endoscopic retrograde biliary drainage was effective and safety for malignant biliary obstruction.

关 键 词：经内镜胆道支架引流术 胆道梗阻 恶性 黄疸 

分 类 号：R575[医药卫生—消化系统]