杭白菊复合饮驱铅效果评价  

Evaluation on effect of chrysanthemum compound drink on decreasing lead content

作　　者：李伟[1] 范广勤[1] 

机构地区：[1]南昌大学医学院实验教学部,南昌330006

出　　处：《中国公共卫生》2007年第11期1380-1381,共2页Chinese Journal of Public Health

基　　金：江西省教育厅科技项目(F010706)

摘　　要：目的了解杭白菊复合饮驱铅效果。方法采用小鼠铅负荷增高实验,建立中毒模型。测定各组血铅、骨铅、维生素C指标;另选择血铅高于2.40μmol/L接铅者60名,随机分为试验组与对照组,测定服用杭白菊复合饮前后血铅、尿铅指标。结果驱铅实验组小鼠血铅、骨铅均低于染毒组,差异均有统计学意义(P<0.05)。维生素C含量显著增高(P<0.01),杭白菊复合饮对小鼠血铅、骨铅的铅清除率分别为36.7%,33.4%;接铅者试食杭白菊复合饮服用15 d后与服用前比较血铅下降明显,差异有统计学意义(P<0.01),服用30 d后下降更明显。服用15和30 d后血铅的铅清除率分别为42%,59%。服用15 d后尿铅平均值明显增高,是服用前的2倍,差异有统计学意义(P<0.01)。服用30 d后尿铅排出下降,但与试验前比较差异有统计学意义(P<0.05)。结论杭白菊复合饮驱铅效果满意。Objective To realize comprehensively effect of chrysanthemum compound drink on decreasing lead content. Methods Make toxic animal models throught experiments of load-increasing lead to mice and measure their blood lead, bone lead and vitamin C;60 mice selected whose blood lead was over 2.40μmol/L were randomly divided into experiment group and control group, measure their blood lead and urine lead before and after intake of chrysanthemum compound drink. Results Levels of blood lead and bone lead in intervention group were lower than those in control group, which were both significant different（ P 〈 0.05） ;Vitamin C contents were also obviously raised. The rate of eliminating blood lead and bone lead were 36.7 % and 33.4 %. After the mice fed chrysanthemum compound drink for 15 days, the blood leads were lower obviously than those before eating. The mean of urine leads was two times than before. These were all significant different（ P 〈 0.01 ）. After 30 days, the decrasing of blood lead was more obvious and urine blood were declined, but they were signifcant different than that before test（ P 〈 0.05）. Rates of eliminating blood lead 15 days and 30 days were 42 % and 59 %. Conclusion The effect of chrysanthemum compound drink on decreasing lead content is good.

关 键 词：杭白菊 铅 驱铅效果 

分 类 号：R155.59[医药卫生—营养与食品卫生学]