龙血竭胶囊的体外抗氧化研究  

In vitro antioxidant properties of Longxuejie Capsule

作　　者：师梅梅[1] 杨建雄[1] 

机构地区：[1]陕西师范大学生命科学学院,陕西西安710062

出　　处：《中成药》2007年第11期1591-1594,共4页Chinese Traditional Patent Medicine

基　　金：国家自然科学基金资助项目(20175012)

摘　　要：目的:研究龙血竭胶囊(血竭)的体外抗氧化作用。方法:通过一系列的体豌分析体系,包括DPPH·/O2-·/·OH自由基清除体系,还原能力分析体系,Fe2+诱导的脂质过氧化反应和β-胡萝卜素/亚油酸自氧化体系,研究龙血竭胶囊的体外抗氧化活性。结果:龙血竭胶囊能够清除DPPH·、O2-·和·OH自由基,具有一定的还原能力,并且可以有效抑制Fe2+诱导的脂质过氧化反应和β-胡萝卜素/亚油酸的自氧化。结论:龙血竭胶囊具有明显的体外抗氧化活性。AIM： T6 evaluate the antioxidant properties in vitro of Longxuejie Capsule （Sanguis draconis） （LC）. METHODS： The antioxidant activities of Longxuejie Capsules were investigated by employing several ex- ternal assay systems, including l, 1-diphenyl-2-picrylhydrazyl （DPPH · ）/peroxide anion/hydroxyl radical-scaven- ging, reducing power assay system, peroxidation of polyunsaturated fatty acid from yolk lipoprotein induced by Fe^2＋ method, and β-carotene/linoleic acid assay system. RESULTS： The LC showed scavenging activity against free radicals, such as DPPH · , peroxide anion and hydroxyl radicals. LC also exhibited effective reducing power and powerful inhibitory effects on peroxidation of polyunsaturated fatty acid from yolk lipoprotein induced by Fe^2＋. Fur- thermore, LC showed markedly inhibitory effect on β-carotene/linoleic acid assay system. CONCLUSION： Longxuejie Capsule has obvious antioxidant activities in vitro

关 键 词：龙血竭胶囊 体外抗氧化 超氧自由基 羟自由基 DPPH 

分 类 号：R285.6[医药卫生—中药学]