血管活性肠肽在中枢神经系统疾患作用的研究  

The Effect of Vasoactive Intestinal Peptide on Central Nervous System Diseases

作　　者：井丽娟[1] 汤勇[2] 于哩哩[1] 毕长柏[1] 王熙梅[1] 

机构地区：[1]河北省人民医院儿科,石家庄050071 [2]北京空军总医院核医学科

出　　处：《天津医药》1997年第6期348-350,共3页Tianjin Medical Journal

摘　　要：对30例急性脑炎脑病患儿的血浆和脑脊液(CSF)血管活性肠肽(VIP)含量进行了放免测定,并对其中11例CSF VIP进行了复查。结果表明,急性期血浆和脑脊液VIP水平均明显高于对照组(P<0.001),随着病情好转CSF VIP仍在较高水平维持2～3周。死亡患儿临终前CSFVIP水平多呈低值,提示VIP水平可作为病情严重程度的参考指标。The levels of vasoactive intestinal peptide(VIP) in both plasma and cerebrospinal fluid were measured by radioimmunoassay in 30 children with acute encephalitis-encephalopathy , and 11 cases were serially reexamined. The results showed that the VIP levels in both plasma and cerebrospinal fluid were elevated in study group than in control group (P<0. 001). The high levels of VIP were usually kept for 2 - 3 weeks;but the levels were generally lower in the terminal stage. It was suggested that the VIP may be serve ask reference index of patient's condition.

关 键 词：血管活性肠肽 脑疾病 脊髓疾病 

分 类 号：R742.02[医药卫生—神经病学与精神病学] R744.02[医药卫生—临床医学]