1例肺上皮样血管肉瘤临床病理分析  

Clinicopathologic analysis of pulmonary epithelioid angiosarcoma

作　　者：祁敏现[1] 李建军[1] 盛喜玲[2] 

机构地区：[1]河南省胸科医院,郑州450008 [2]河南省疾病预防控制中心

出　　处：《中原医刊》2007年第21期87-88,共2页Central Plains Medical Journal

摘　　要：目的 探讨肺上皮样血管肉瘤的病理形态、免疫组化特点及常见的鉴别诊断。方法 应用常规病理及免疫组织化学方法,对肺上皮样血管肉瘤进行形态及免疫标记研究。结果 肺上皮样血管肉瘤表现为有不规则的不成熟血管形成区或原始血管腔,在无明显血管形成区,可见有裂隙的实性区或网状区,常伴有出血坏死。免疫组化CD31（＋）、CD34（＋）、CK（＋）。结论 肺上皮样血管肉瘤具有软组织上皮样肉瘤的特点,是血管肉瘤的一种特殊类型。CD31、CD34是敏感性较高的标记物。熟悉其形态特征对避免误诊具有重要意义。Objective To study the characteristics of pathologic morphology,immunohistochemistry of epithelioid angiosarcoma （EA） and it＇s common differential diagnosis. Methods Routine pathologic method and immunohistochemistry were used. Results The tumor cell of EA formed irregular and immature blood lumen or intracytoplasmic lumens,intercommunicating vascular channels formed by tumor cell in solid area, and with hemorrhage and necrosis, immunohistochemical staining showed tumor cell were positive for CD31 ,CD34 cytokeratin. Conclusion Pulmonary primary EA has the same feature with the EA in soft tissue,is a variant of angiosareoma ; CD31, CD34 are more sensitive marker. Recognizing its morphological characteristics is important to avoid confusion with other similar lesions.

关 键 词：肺 上皮样血管肉瘤 免疫组织化学 

分 类 号：R734[医药卫生—肿瘤]