河南省农村地区胃癌危险因素的病例对照家系研究  

A case-control family study of gastric cancer in Henan province

作　　者：金湘东[1] 代丽萍[2] 张建营[2] 张校辉[2] 王鹏[2] 聂轶飞 王平[2] 徐学琴[2] 王凯娟[2] 

机构地区：[1]郑州铁路职业技术学院护理系,郑州450052 [2]郑州大学公共卫生学院流行病学教研室

出　　处：《中南大学学报（医学版）》2007年第5期782-785,共4页Journal of Central South University ：Medical Science

基　　金：国家自然科学基金(30640072);河南省杰出人才创新基金(0621002500)~~

摘　　要：目的:探讨河南农村地区胃癌发生的危险因素。方法:确定胃癌病例家系和对照家系各325户,每组1010人,以家庭为单位入户面访方式收集人群资料。应用单因素和多因素非条件logistic回归分析探讨不同因素对胃癌发病的影响。结果:胃不适症状、暴饮暴食、口味重、吃剩饭>3次/周、精神刺激史等因素在病例家系与对照家系的分布中差异具有统计学意义。结论:胃不适症状、暴饮暴食、口味重、吃剩饭>3次/周、精神刺激史等因素是病例家系成员发生胃癌的危险因素。Objective To explore the risk factors of gastric cancer in the rural area of Henan province. Methods Three hundred and twenty-five families with gastric cancer and 325 control families （1 010 persons in each group ） were selected among the rural residents in 4 counties of Henan province. Totally 2 020 people were surveyed and assessed using population-based case-con- trol family study. Results Gastric cancer was related to stomach upset, irregular dietary, hobby for salty taste, residual food, and history of mental stimulus. Conclusion Stomach upset, irregular dietary, hobby for salty taste, residual food, and history of mental stimulus are the risk factors of gastric cancer.

关 键 词：胃癌 病例对照家系设计 危险因素 

分 类 号：R735.2[医药卫生—肿瘤]