乳腺癌保乳手术切缘宽度为2cm与3cm的疗效比较  

Breast conserving operation for breast cancer with 2 cm and 3 cm incision margins:a comparison of outcomes

作　　者：于跃[1] 施俊义[1] 盛湲[1] 李莉[1] 胡薇[1] 

机构地区：[1]第二军医大学长海医院普通外科,上海200433

出　　处：《第二军医大学学报》2007年第11期1229-1231,共3页Academic Journal of Second Military Medical University

摘　　要：目的:研究乳腺癌患者局部扩大切除术中切缘宽度与生存率、局部复发率和术后乳房美容效果之间的关系。方法:回顾了我院42例行切缘宽度为2cm的局部扩大切除术的病例和37例行切缘宽度为3cm的局部扩大切除术的病例,计算并比较两组病例治疗后5年生存率、10年生存率、5年复发率、10年复发率和术后乳房的美容效果。结果:两组病例在5年生存率、10年生存率、5年局部复发率及10年局部复发率均无统计学差异。在美容效果上,评分优良率2cm组(90.5%)要优于3cm组(73.0%),两者存在统计学差异(P<0.05)。结论:行局部扩大切除术时,切缘宽度2cm已基本足够,无需进一步扩大切缘宽度,否则可能会降低术后乳房美容效果。Objective：To explore the relationship between margin width in extended lumpectomy for breast cancer with survival rate, local recurrence rate,and cosmetic result. Methods： The clinical data of 42 breast cancer patients who had a 2 cm incision margin width （group A） and 37 who had a 3cm incision margin width （group B） were retrospectively analyzed. The 5-year, 10-year survival rates, recurrence rates, and the cosmetic results were compared between the 2 groups. Results： The 5-year and 10-year survival rates in patients of group A were 90. 1% and 85.3%, respectively; in patients of group 13 were 92. 3% and 83.6%, respectively（P〉0.05）. The 5-year and 10-year local recurrence rates in patients of group A were 5.9% and 11.6%, respectively; in patients of group B were 3.4 % and 12.9 %, respectively（P〉0.05）. The cosmetic result was significantly better in group A than that in group B（P〈0.05）. Conclusion： An incision margin width of 2 cm is enough for extended lumpectomy. It is not necessary to further expand the margin width; otherwise, it may influence the cosmetic results after operation.

关 键 词：乳腺肿瘤 保留乳房手术 切缘宽度 对比研究 

分 类 号：R737.9[医药卫生—肿瘤]