神经衰弱患者免疫功能变化初探  

Preliminary study on immunologic function change in neurasthenic patients

作　　者：刘楠[1,2] 郑安[1,2] 余启胜[1,2] 黄华品 

机构地区：[1]福建医科大学附属协和医院 [2]福建医科所

出　　处：《中国行为医学科学》1997年第2期106-107,共2页Chinese Journal of Behavioral Medical Science

摘　　要：目的观察神经衰弱患者细胞免疫和体液免疫指标的变化。方法以３８例神经衰弱患者为试验组，另设相应年龄段的健康人为对照组，以致敏羊红细胞花环试验直接法、死活菌鉴别染色法、琼脂单扩散法、聚乙二醇浊度法，分别验测了Ｔ细胞亚群、中性粒细胞功能试验、血清ＩｇＧ、ＩｇＡ、ＩｇＭ、Ｃ３、Ｃ４含量及ＣＩＣ测定。两组样品均数采用ｔ检验分析。结果神经衰弱患者外周血ＣＤ＋３％、中性粒细胞吞噬率均显著低于对照组（Ｐ＜０．００１），血清ＩｇＡ水平低于对照组（Ｐ＜０．００１），血清Ｃ４水平显著升高（Ｐ＜０．０５）。结论本病确实存在免疫功能紊乱的现象。Objective To observe the change of Cyto immunity and humoral immunity in the neurasthenic patients. Methods T lymphocytes subsets、Neutrophil function test、IgG、IgA、IgM、C3、C4 in sera and CIC were detected in 38 neurasthenic patients and normal controls. The means of two group were analysed by t test. Results the number of CD + 3,the Neutrophil phagocytosing rate and IgA in sera significantly decreased (P<0.001), and C4 in sera significantly increased (P<0.05) compared with the controls. Conclusion The results indicated that the disorder of immunological function had alreadly existed in the neurasthenic patients.

关 键 词：神经衰弱 免疫功能 

分 类 号：R749.710.3[医药卫生—神经病学与精神病学]