FACT-G问卷评估影响胃肠道恶性肿瘤患者生命质量的相关因素  

Factors Affecting the Quality of Life in Gastrointestinal Cancer Patients Measured by FACT-G Questionnaire

作　　者：陈鹏[1] 王海江[1] 朱琳[2] 凤小花[1] 贾蕊[1] 

机构地区：[1]新疆医科大学附属肿瘤医院腹部外科,新疆乌鲁木齐830011 [2]新疆医科大学附属肿瘤医院科研科,新疆乌鲁木齐830011

出　　处：《苏州大学学报（医学版）》2007年第5期783-786,792,共5页Suzhou University Journal of Medical Science

摘　　要：目的评估胃癌、大肠癌患者的生命质量,探讨与之相关的影响因素。方法采用癌症治疗功能评价系统量表体系中的共性模块(FACT-G)调查了52例胃癌患者和50例大肠癌患者。各影响生命质量因素的差异程度经t检验及方差分析处理,对不同年龄、性别、文化程度、病种、病期及经过治疗与否的患者的FACT-G得分进行比较。运用最优尺度回归分析、多重线性回归分析和判别方程了解生命质量各个子量表与病期的关系。结果较早期患者及经过综合治疗后的患者的生命质量较好;年龄、性别对生命质量的影响不大。FACT-G量表对大肠癌的效度可能要比对胃癌更好;以手术为主的综合治疗措施可在一定程度上提高患者的生命质量。结论生命质量应成为评价恶性肿瘤治疗疗效的指标之一;开展胃肠道恶性肿瘤的生命质量测评对临床诊疗工作有一定的指导意义。Objective To evaluate the quality of life （QOL） of gastric cancer and colorectal cancer patients and to investigate the differences in QOL with respect to social and medical characteristics. Methods Structured questionnaires FACT-G were used in 52 cases of gastric cancer patients and 50 cases of colorectal cancer patient. The T-test and one-way analysis of variance （ANOVA） were used to compare the differences in QOL at a 5% level of significance. Optimal scaling regression, multiple linear regression and discriminant analysis were used to find the relationship of the stages among the do- mains of FACT-G. Results The patients at the early stages, or having experienced the combined therapy, had better QOL. Years of age and sexuality were not able to have an effect in QOL. Maybe FACT-G used for colorectal cancer patients had better validity than that used for gastric cancer patients. Conclusion The QOL should be use as an indicatrix for curative effect evaluation of cancer treatment. The work about quality of life evaluate in gastrointestinal cancer patients suggests that the establishment of QOL judgment standard in Chinese gastrointestinal cancer patients might be useful for clinical work.

关 键 词：生命质量 胃肿瘤 大肠肿瘤 FACT-G 

分 类 号：R735[医药卫生—肿瘤]