慢性肝病、肝硬化并发感染性休克临床分析  

Chronic Hepatitis and Cirrhosis Complicated with Septic Shock:A Clinical Analysis

作　　者：江宇[1] 刘刚[1] 龚玲[1] 金益辉[1] 张友才[1] 陈永平[1] 

机构地区：[1]温州医学院附属第一医院,浙江温州325000

出　　处：《中华医院感染学杂志》2007年第11期1365-1367,共3页Chinese Journal of Nosocomiology

摘　　要：目的探讨慢性肝病、肝硬化并发感染性休克患者临床特征及预后转归情况。方法回顾性分析2002年1月-2005年8月,医院收治的45例慢性肝病、肝硬化并发感染性休克患者临床资料,采用SPSS13.0进行统计学分析。结果45例慢性肝病、肝硬化患者中原发感染为腹腔及肠道感染18例(40.0%);并发急慢性肝功能衰竭30例(66.7%);分泌物培养常见病原菌依次为大肠埃希菌(31.6%)、葡萄球菌属(23.7%)、假单胞菌属(18.4%)、假丝酵母菌属(10.5%)、弧菌属(7.9%)。结论慢性肝病、肝硬化感染性休克原发感染以腹腔及肠道感染为主,病原菌分析革兰阴性菌比例增大,一旦发生感染性休克,极易并发急慢性肝衰竭至死亡。OBJECTIVE To study the clinical characteristics and prognosis of chronic hepatitis and cirrhosis complicated with septic shock. METHODS Forty-five cases with chronic hepatitis and cirrhosis complicated with septic shock were observed. SPSS software was used for statistical analysis. RESULTS The infected sites were abdominal cavity and intestinal tract（66. 70/00） in 45 cases. Thirty cases complicated with hepatic failure were found. Escherichia coli rated the first（31.6%）, fotlowed by Staphylococcus（23. 7%）, Pseudomonas （18. 4%）, Candida （10.5 % ）, and Vibrio （7.9 %） in secretion analysis. CONCLUSIONS The sites easiest to be attacked with infection are abdominal cavity and intestinal tract in these patients. The rate of Gram-negative bacilli is increasing. In these patients acute and acute-to-chronic hepatic fail＇are are common. The death rate is high in these patients.

关 键 词：感染性休克 肝硬化 肝衰竭 

分 类 号：R575.2[医药卫生—消化系统]