糠偶姻单酯类化合物的合成  

Synthesis of Monoester Compounds of Furoin

作　　者：张峰[1] 孙继奎[1] 李亚卓[1] 高大维[1] 张玉敏[1] 赵天琦[1] 陈晓东[2] 

机构地区：[1]吉林大学化学学院,长春130012 [2]吉林大学测试科学实验中心

出　　处：《应用化学》2007年第12期1461-1463,共3页Chinese Journal of Applied Chemistry

基　　金：吉林省科技厅资助项目(1999010540)

摘　　要：以糠醛为基础原料,经维生素B1催化合成糠偶姻,再由糠偶姻分别和乙酰氯、月桂酰氯、苯甲酰氯、α-呋喃甲酰氯和3-α-呋喃烯丙酰氯反应,在NaOH/无水THF体系中,于水浴回流条件下合成了相对应的糠偶姻单酯类化合物。醋酸糠偶姻酯(1)、月桂酸糠偶姻酯(2)、苯甲酸糠偶姻酯(3)、α-呋喃甲酸糠偶姻酯(4)和3-α-呋喃丙烯酸糠偶姻酯(5)的收率以糠偶姻计算,分别为99.3%、96.5%、98.0%、99.4%和98.7%。并通过元素分析、Mass谱、1HNMR谱对所合成的目标产物(1、2、3、4和5)分别进行了表征。Furoin was synthesized from furol with VB1 as the catalyst, which was then reacted with acetyl chloride, lauroyl chloride, benzoyl chloride, α-furoyl chloride and 3-α-furyl acryloyl chloride, respectively; corresponding monoester compounds of furoin were synthesized in THF in the presence of sodium hydroxide under reflux. The yields of compounds 1, 2, 5, 4, and 5 based on furoin were 99. 3% , 96. 5% , 98. 0% , 99. 4% and 98.7%, respectively. By characterization with elementary analysis, Mass spectrum and 1H NMR, the structures of the target products were characterized by elemental analysis, MS and ^1H NMR.

关 键 词：糠偶姻 乙酰氯 月桂酰氯 苯甲酰氯 α-呋喃甲酰氯 α-呋喃烯丙酰氯 酯化 合成 

分 类 号：O626.1[理学—有机化学]