A Novel Stereoselective Synthesis of （1Z,3E）-2-Phenyl（or p-Tolyl）sulfonyl-substituted 1,3-Dienes via Palladium Catalyzed Cross-coupling Reactions of （E）-α-lodovinyl Sulfones  

作　　者：胡荣华 陈桂琴 蔡明中 

机构地区：[1]Department of Chemistry, Jiangxi Normal University, Nanchang, Jiangxi 33002 7, China [2]Department of Chemistry, Jinggangshan University, Ji'an, Jiangxi 343009, China

出　　处：《Chinese Journal of Chemistry》2007年第12期1927-1931,共5页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China （No. 20462002） and the Natural Science Foundation of Jiangxi Province in China （No. 0420015）.

摘　　要：（E）-α-Stannylvinyl phenyl（or p-tolyl）sulfones underwent an iododestannylation reaction to afford （E）-α-iodovinyl phenyl（or p-tolyl）sulfones 1, which reacted with （E）-alkenylzirconium（IV） complexes 2 produced in situ by hydrozirconation of terminal alkynes in the presence of a Pd（PPh3）4 catalyst to afford stereoselectively （1Z,3E）-2- phenyl（or p-tolyl）sulfonyl-substituted 1,3-dienes 3 in good yields.（E）-α-Stannylvinyl phenyl（or p-tolyl）sulfones underwent an iododestannylation reaction to afford （E）-α-iodovinyl phenyl（or p-tolyl）sulfones 1, which reacted with （E）-alkenylzirconium（IV） complexes 2 produced in situ by hydrozirconation of terminal alkynes in the presence of a Pd（PPh3）4 catalyst to afford stereoselectively （1Z,3E）-2- phenyl（or p-tolyl）sulfonyl-substituted 1,3-dienes 3 in good yields.

关 键 词：（E）-α-iodovinyl sulfone HYDROZIRCONATION 1 3-dien-2-yl sulfone palladium CROSS-COUPLING 

分 类 号：O6[理学—化学]