氯乙酸酯的微波绿色合成  

Microwave-assisted Green Synthesis of Chloroacetate

作　　者：张志广[1] 夏然[1] 渠桂荣[1] 

机构地区：[1]河南师范大学化学与环境科学学院,河南新乡453007

出　　处：《河南师范大学学报（自然科学版）》2007年第4期92-94,共3页Journal of Henan Normal University(Natural Science Edition)

基　　金：国家自然科学基金(20372018)

摘　　要：在微波辐射功率为250W反应10min的条件下，氯乙酸分别与甲醇、乙醇、丙醇、异丙醇、叔丁醇在NaHSO4·H2O催化下顺利发生酯化反应，以76％-91％产率得到了相应的氯乙酸酯化合物，该方法具有操作简单，催化剂可重复使用，反应时间短，对环境友好等优点，产物结构经^1H-NMR和元素分析确认。Using NaHSO4·H2O as the catalyst, chloroacetate derivatives were obtained in 76%-91% yields from chloroacetic acid and corresponding alcohol under microwave irradiation at 250 W for 10 rain. This method has the advantages of easy manipulation, reuse of the catalyst, short reaction time, and friendly to environment. All products were identified by ^1H NMR and elementary analysis.

关 键 词：微波辐射 氯乙酸酯 绿色合成 

分 类 号：O625.75[理学—有机化学]