胰腺、后腹膜及椎旁癌肿疼痛的介入化疗应用  

Interventional chemotherapy for pain caused by pancreatic, retro-peritoneal and paravertabral tumors

作　　者：茅爱武 胡旋 刘诗义 贾一平 王振磊 方世明 高中度 

机构地区：[1]上海长宁区同仁医院介入中心,200050

出　　处：《介入放射学杂志》2007年第11期769-771,共3页Journal of Interventional Radiology

基　　金：上海市科学发展研究基金项目(024119069)

摘　　要：目的探索胰腺、后腹膜及椎旁癌肿疼痛的介入止痛方法,以微创技术缓解晚期癌痛。方法对86例晚期癌症因原发或转移病变侵及后腹膜、纵隔和椎旁以及脊柱引起剧烈疼痛患者,应用介入微创技术经腰动脉、肋间动脉和其他肿瘤供养血管插管行化疗药物灌注治疗。随访术后病情变化及疼痛缓解情况。结果治疗后患者肿瘤生长得以抑制,疼痛症状明显缓解或减轻。应用数字分级及主诉分级两种评分法同时评估,疼痛缓解有效率分别达90.7%和88.4%。结论腰、肋动脉化疗药物灌注能有效缓解因后腹膜、纵隔或椎旁以及脊柱病变引起的癌性疼痛,可作为临床可供选择的方法予以应用。Objective To probe an interventional method in treatment of cancerous pain in late-stage cancers of pancreas, retroperitoneal and paravertabral space by micro-injury technique. Methods 86 cases of late-stage cancer （primary or metastatic）with severe pain caused by the invasion to the retroperitonium, paravertabral space and spine; were performed by microinvasive selective parent vascular catheterization perfusion chemotherapy through lumbar and intercortal arterial approach. Follow up of the relief of symptoms and pain were carried out. Results The inhibition of tumor growth and the symptoms relief were obtained obviously. The effeciency rates for pain-relief were 90.7% and 88.37%, evaluated by number-grading and complain-grading respectively. Conclusion The arterial perfusion chemotherapy can effectively relieve the cancerous pain caused by retro-peritoneum, mediastinal, spinal and paravertabral troubles, providing a method of choice clinically.

关 键 词：腰动脉 肋间动脉 癌性疼痛 化疗灌注 

分 类 号：R730.5[医药卫生—肿瘤]