埋植式动脉泵化疗与口腔鳞癌的综合治疗  

The chemotherapy of subcutaneous implantable pump system and the combined treatment of oral squamous cell carcinomas

作　　者：李瑞春 华成舸[2] 唐休发[2] 刘婷 

机构地区：[1]渭南市中心医院口腔科,陕西渭南714000 [2]四川大学华西口腔医院头颈肿瘤外科,四川成都610041

出　　处：《现代肿瘤医学》2007年第9期1247-1248,共2页Journal of Modern Oncology

摘　　要：目的:探讨埋植式动脉泵在口腔鳞癌化疗中的效果及在口腔鳞癌综合治疗中的应用价值。方法:采用ZW埋植式动脉泵经颈外动脉插管治疗口腔鳞癌29例,观查化疗效果及其与手术、放疗综合应用的可行性。结果:埋植式动脉泵给药治疗口腔鳞癌的有效率87.5%,未出现明显毒副作用。结论:埋植式动脉泵是口腔鳞癌化疗给药方法的较好选择,可作为多药物、多周期单一化疗;术前诱导及术后辅助化疗;化疗与放疗联合应用,多手段综合治疗中化疗最佳途径,可在临床广泛应用。Objective：To investigate the effect of chemotherapy of the subcutaneous implantable pump system（SIPS）and its value in the combined treatment of oral squamous cell carcinomas. Methods： The SIPS was employed in the chemotherapy through the external carotid artery for 29 patients with oral squamous cell carcinomas.The response was assessed. The effect of SIPS chemotherapy in combination with operation and radiotherapy was evaluated. Results： The overall effective rate after SIPS chemotherapy was 87.5% .No obvious side effects were observed .The procedure of SIPS was simple alowed a long period for use. Conclusion： The SIPS is one of the best ways to perform chemotherapy for oral squamous cell carcinomas. It is valuable for single chemotherapy with multiple drugs and cycles, for assistant chemotherapy before and after operation ,and for chemotherapy combined with radiotherapy.

关 键 词：埋植式动脉泵 化疗 口腔鳞癌 

分 类 号：R739.8[医药卫生—肿瘤]