放射治疗配合微波热疗在颈部淋巴结转移癌的临床应用  

Analysis for treatment of metastatic neck node cancer with hyperthermia and radiotherapy

作　　者：黄梅芳[1] 张灿珍 杨丽芳[1] 郎平[1] 郑红霞[1] 张志军[1] 邓省益 王振波[1] 

机构地区：[1]云南省曲靖市第一人民医院肿瘤科,云南曲靖655000

出　　处：《现代肿瘤医学》2007年第10期1402-1403,共2页Journal of Modern Oncology

摘　　要：目的:探讨微波热疗配合放射治疗对颈部淋巴结转移癌局部控制率的临床应用价值。方法:对2004年10月～2006年5月收治的资料较全的52例颈部淋巴结转移癌(N2～N3)病人随机分为两组,对照组仅行单纯常规放疗,局部总剂量DT(66～70)Gy/6.5W～7W;联合组除常规放疗外同期配合微波热疗每周3次(周1、3、5),温度控制在(42±1)℃,每次(30～40)分钟,(2～3)周为一疗程,平均每人7.3次。结果:联合组总显效率及完全缓解率均明显高于对照组(P<0.05);且联合组在起效时间上也明显短于对照组(P<0.01),有非常显著性差异。结论:微波热疗对放疗有协同增敏作用,二者配合对颈部较大的淋巴结转移癌可明显提高局控率,减少局部放疗剂量,减轻放疗反应,无明显毒副作用;值得临床推广使用。Objective：To investigate the effective value of treating with combination hyperthermia and radiotherapy for metastatic neck node cancer.Methods：From 2004 to 2006,52 patients of neck metastatic cancer（N2~N3） were divided into two groups.Placebo group was only treated by regular radiotherapy and the total dose（TD） was（66~70）GY/6.5w^7w.Combined group was treated with regular radiotherapy and microwave thermotherapy.The patients received hyperthermia three times per week.The thermometer was controlled in（42±1）℃ and for（30~40） minutes every time.Results：Combined group was much better than radiotherapy group in total effective rate and completely rate,and the time of effect also shorten compared with radiotherapy group.Conclusion：The combination of two methods is efficient and the effect of treatment is significantly improved by radiotherapy combined with thermotherapy than only radiotherapy.

关 键 词：放射治疗 温热疗法 颈部转移癌 临床应用 

分 类 号：R733.4[医药卫生—肿瘤]