关于适合我国EALES病特点的临床分期标准的研究  

Clinical Staging System of Eales Disease

作　　者：周必业[1] 魏世辉[1] 

机构地区：[1]解放军总医院眼科,北京100853

出　　处：《中国实用眼科杂志》2007年第10期1078-1080,共3页Chinese Journal of Practical Ophthalmology

基　　金：吴阶平医学基金资助项目（NO.2003-32-D）

摘　　要：目的制定出符合我国Eales病患者的分期标准,能够给临床诊断、治疗以及EALES病的研究提供一个客观依据。方法对解放军总医院Eales病患者的病历料作回顾性分析,结合患者病史、临床表现、治疗方案等,结合我国Eales病患者的临床特点,制定一个新的适合临床应用的分期标准。Eales病包括以下四个时期：1期：炎症期：小静脉和大静脉的血管周围炎,伴有视网膜浅层出血。2期：缺血期：毛细血管无灌注。3期：增殖期：视盘和/或视网膜的新生血管,纤维血管增殖和玻璃体出血。4期：并发症期：牵拉性或联合性视网膜脱离（牵拉性合并孔源性）,黄斑前膜,新生血管性青光眼,并发性白内障。结果这种新的分期标准简便、实用。这种新的分期标准提示了该疾病的严重程度。玻璃体出血是所有患者中最多见的临床表现。结论这种新的分期标准能够客观地对疾病进行分级,并能评价该病的严重程度。通过对就诊患者疾病的分期,医生可以更客观地选用不同的治疗方案。这个分期标准的制定,对于规范和推进Eales病的医疗和科研能起到一定的作用。Purpose Todevelop and standardize a universally acceptable new staging system of Eales diseaseMethods A new staging system was established and standardized based on standard terminology and features. Eales disease consisted of 4 stages. Stage 1 is periphlebitis of small and large caliber vessels with superficial retinal haemorrhages. Stage 2 is capillary non perfusion and neovascularization elsewhere/of the disc. Stage 3 is classified as fibrovascular proliferation and vitreous haemorrhage. Stage 4 is traction/combined rhegmatogenous retinal detachment,macular epiretinal membranes,neovascular glaucoma,complicated cataract. Results The new staging system was consistent,simple and easy to recall.The new staging system also defined the severity of the disease.Vitreous haemorrhage was found to be the commonest presenting feature（34. 1%）.Conclusions The new staging system is useful in classifying and assessing the severity of disease.Management strategy can also be defined according to the stage of the disease.It is designed to promote the use of standard assessment with applications to clinical management and research.key words

关 键 词：特发性视网膜静脉周围炎 玻璃体出血 分期 

分 类 号：R774.1[医药卫生—眼科]