华南地区与西南地区先天性青光眼临床特点的比较  

A comparison study on clinical features of primary congenital glaucoma between Southern and Southwest China

作　　者：杜绍林[1] 张秀兰[1] 李昂[1] 祝芸芸[1] 滕蕾蕾[1] 彭寿雄[1] 葛坚[1] 

机构地区：[1]中山大学中山眼科中心,眼科学国家重点实验室,广州510060

出　　处：《中国实用眼科杂志》2007年第11期1218-1220,共3页Chinese Journal of Practical Ophthalmology

基　　金：教育部回国人员科研启动基金资助项目（教外司留2005-55）

摘　　要：目的通过对中山眼科中心与华西医院眼科中心收治的原发性先天性青光眼患者进行对比,探讨我国华南、西南地区先天性青光眼发病的异同性。方法以华西医院眼科中心（WCHOC）报道的原发性先天性青光眼的研究结果为参照,与中山眼科中心（ZOC）在同一时段（2002年1月至2004年12月）收治的原发性先天性青光眼患者进行回顾性对比分析。结果ZOC入组的原发性先天性青光眼患者有51例（102眼）,WCHOC患者40例（80眼）。两组患者均以男性为多,分别为3.25：1和2.07：1;双眼发病为主：家族史均不明显;发现年龄在两地患者中无显著性差异（P〉0.01）：但WCHOC患者就诊年龄远远大于ZOC患者（分别为36个月与9个月）;就诊时已有视功能严重损害者以WCHOC患者为多：手术治疗均以小梁切开联合小梁切除术为主。结论与中山眼科中心原发性先天性青光眼患者比较,华西眼科中心患者就诊较晚,视功能损害严重,诊断、治疗相对滞后。在一定程度上可能与地区经济水平对该病诊治的影响有关。中国先天性青光眼的防治工作仍存在很大的不平衡性,值得关注。Objective To investigate the differences between Southern and Southwest Chinese primary congenital glaucoma patients. Methods The clinical features of primary congenital glaucoma patients in two different hospitals were compared between Zhongshan Ophthalmic Center （ZOC） and West China Hospital Ophthalmic Center （WCHOC）. Results There were 51 cases （102eyes） in ZOC group and 40 cases （80eyes） in WCHOC group. There was a male preponderance in both ZOC and WCHOC patients. The sex ratio （male to female） was about 3.25：1 and 2.07：1,respectively. Bilateral attack was seen in most patients. There was no clear family history related. The age which was complained of symptoms and signs was not significant different in both ZOC and WCHOC patients. However,the age when was received medical diagnosis had remarkable differences （36 months and 9 months,respectively）. The visual function was found severely damaged in most WCHOC patients. The strategies of clinical management were similar in both hospitals. Conclusion WCHOC patients had a relatively delayed diagnosis,more severe visual function damage and a delayed management. More attempts on prevention and treatment are needed in Chinese primary congenital glaucoma.

关 键 词：原发性先天性青光眼 回顾性分析 临床特点 

分 类 号：R775.4[医药卫生—眼科]