低位直肠癌经内外括约肌间切除术后直肠肛管向量测压的研究  

Anal Sphincteric Function Assessment of Intersphincteric Resection for Low Rectal Cancer by Vectorial Manometry

作　　者：丛进春[1] 戴显伟[1] 张宏[1] 陈春生[1] 刘恩卿[1] 

机构地区：[1]中国医科大学附属盛京医院肛肠外科,沈阳110004

出　　处：《中国普外基础与临床杂志》2007年第6期634-638,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：辽宁省教育厅高等学校科学技术研究项目(编号:05L484)~~

摘　　要：目的应用直肠肛管向量测压技术评估低位直肠癌经内外括约肌间切除术后肛门括约肌功能。方法对16例行经内外括约肌间切除术的低位直肠癌患者行直肠肛管向量测压,并选择同期30例直肠癌低位前切除术患者及30例肛门功能正常的健康人作为对照研究。结果根据临床症状将经内外括约肌间切除术后患者分为污便组和排便功能良好组,其肛管最大压力、向量容积及对称指数均显著低于正常对照组及低位前切除术对照组(P<0.001);污便组的最大收缩压、收缩向量容积及对称指数明显低于排便功能良好组(P<0.001);行经内外括约肌间切除术后25.0%(4/16)的患者出现直肠肛门抑制反射,明显低于行低位前切除术患者的93.3%(28/30),P<0.001。结论经内外括约肌间切除术后患者肛管最大压力及向量容积下降,肛门功能不如行低位前切除术者。直肠肛管向量测压技术是评估低位直肠癌患者行经内外括约肌间切除术后肛门括约肌功能较客观的方法。Objective To assess the anal sphincteric function after intersphincteric resection for low rectal cancer by vectorial manometry. Methods Maximal anal pressure, vector volume, vector symmetric index and rectal anal inhibitory reflex were assessed in 16 patients underwent intersphincteric resection for low rectal cancer from 1999 to 2006. Thirty patients with low anterior resection for rectal cancer and another 30 healthy individuals were selected as control. Results The patients in intersphincteric resection group were subdivided into soiling group and defecation function good group. Maximal pressure, vector volume and vector symmetric index of the patients in soiling group and defecation function good group were significantly lower than those of the healthy and low anterior resection controls （P〈0. 001）. The maximal systole pressure, systole vector volume and vector symmetric index in soiling group were significantly lower than those in function good group （P〈0. 001）. The 25.0 % patients in intersphincteric resection group had rectal anal inhibitory reflex, was significantly lower than that of the low anterior resection control group （93.3%, P〈0. 001）. Conclusion The maximal pressure and vector volume are compromised in patients underwent intersphincteric resection . The vectorial manometry can be an objective comprehensive tool for the evaluation of anal sphincter function in patients with intersphincteric resection.

关 键 词：低位直肠癌 经内外括约肌间切除术 直肠肛管向量测压 

分 类 号：R735.37[医药卫生—肿瘤]