脑梗死恢复期患者胃运动功能与胃肠激素的关系  

A study on gastric motor function and gastrointestinal hormones in the patients with convalescence cerebral infarction

作　　者：张英剑[1] 王萍[2] 李变红[1] 乔娜娜[1] 金建军[1] 赵双琴[1] 

机构地区：[1]河南科技大学第一附属医院,河南洛阳471003 [2]河南科技大学医学院

出　　处：《山东医药》2007年第34期13-15,共3页Shandong Medical Journal

基　　金：河南科技大学青年科学基金项(2006QN040)

摘　　要：目的探讨脑梗死恢复期患者胃运动功能与胃肠激素的关系。方法测定脑梗死恢复期患者的血中一氧化氮(NO)、胃泌素(GAS)及胃动素(MTL),检查其胃排空功能及胃电节律变化,并与健康者进行对照。结果与对照组比较,脑梗死组血清NO降低,GAS升高,MTL升高,胃排空功能延迟,胃电节律降低,均以恢复期第7天明显(P均<0.05)。结论脑梗死恢复期患者胃肠激素发生改变,有胃排空障碍及胃电节律紊乱,两者间有一定关系。[ Objective ] To investigate the relation between gastric motor function and gastrointestinal hormones in the patients with convalescence cerebral infarction. [ Methods] The fasting blood levels of gastrin ,motilin and nitric oxide were measured in order to know about the changes of gastrointestinal hormones in the patients with convalescence cerebral infarction. Gastric emptying was measured by radiopaque barium marker mixed standard test meal method. Gastric myoelectrial activity was recorded by cutaneous EGG. [ Results] The serum levels of nitric oxide were significantly lower on the seventh day in group of convalescence cerebral infarction patients than those in control group （ P 〈 0.05 ）, but the serum gastrin levels and the plasma motilin levels were significantly increased （ P 〈 0.05 ）. The seventh day of convalescence cerebral infarction patients showed significantly delayed gastric solid emptying. There were abnormal gastric myoelectrical activities in convalescence cerebral infarction patients. [ Conclusion ] There are some changes of blood gastrin,motilin and nitric oxide levers in the cerebral infarction patients. The delayed gastric solid emptying and abnormal gastric myoelectrical activities are presented in the convalescence cerebral infarction patients.

关 键 词：脑梗塞 胃肠激素类 胃肠活动 

分 类 号：R743.33[医药卫生—神经病学与精神病学]