中、重型溃疡性结肠炎176例临床诊疗分析  

Clinical and therapeautic analysis about 176 cases of moderate type and severe type ulcerative colitis

作　　者：王常会[1] 李福康[1] 林静[1] 

机构地区：[1]泰山医学院附属泰安医院消化内科,山东泰安271000

出　　处：《泰山医学院学报》2007年第5期370-371,共2页Journal of Taishan Medical College

摘　　要：目的评价中、重型溃疡性结肠炎的临床特点及疗效。方法回顾性分析176例中、重型溃疡性结肠炎住院患者的诊疗资料。结果中、重型溃疡性结肠炎患者病变以左半结肠炎型常见,且以初发型及慢性复发型为主。控制急性发作主要药物为糖皮质激素。药物治疗中型、重型溃疡型结肠炎有效率分别为97.3%(144/148)、89.3%(25/28),外科手术率10.7%(3/28)。肠外并发症发生率8.5%(15/176),结肠息肉发生率26.1%(46/176),癌变率2.3%(4/176)。结论正确系统应用糖皮质激素治疗中、重型溃疡性结肠炎疗效显著,但应定期复查结肠镜。Objective： To evaluate the clinical manifestation and curative effect of moderate type and severe type ulcerative colitis （UC）. Methods： 176-cases of hospitalized patients with UC （moderate type and severe type） during 1995 - 2005 were retrospectively reviewed. Results： Patients with UC （moderate type and severe type） were commonly in left-sided colon and were mostly first-onset and chronic recurrent type. The glucocorticoid treatment played the main role in the inducing remission of UC. The effective rate of pharmacotherapy in moderate type and severe type UC were 97.3% （ 144/ 148） and 89.3% （25/28） respectively, and 3-cases （ 10.7% ） were cured by operation. The extraintestinal manifestations, colicpolyps and carcinomatous change were 8.5% （ 15/176）, 26.1% （46/176） and 2.3% （4/176） respectively. Conclusion： The curative effect of treatment UC （moderate type and severe type） with stadard and systematic glucocoticoid is obvious. The patients with UC should be periodically reexaminated by colonoscopy.

关 键 词：溃疡性结肠炎 中型 重型 诊疗分析 

分 类 号：R574[医药卫生—消化系统]