养阴生津方治疗非小细胞肺癌放疗后急性肺损伤的临床研究  

Clinical Study on Yangyin Shengjin Fang for Non small Cell Lung Cancer with Acute Pneumonia after Radiation

作　　者：董红兵 

机构地区：[1]解放军第一五三医院,河南郑州450042

出　　处：《世界中西医结合杂志》2007年第9期526-529,共4页World Journal of Integrated Traditional and Western Medicine

摘　　要：目的:观察养阴生津方治疗非小细胞肺癌放疗后急性肺损伤的临床疗效。方法:选取符合入选标准的患者60例,随机分成观察组30例(西医常规治疗+养阴生津方)、对照组30例(西医常规治疗),主要观察两组临床疗效、症状变化、胸部X线表现、体力状况评分标准(Karnofsky)、体重及症状缓解、激素使用时间等。结果:治疗后观察组总有效率90.00%;对照组总有效率60.00%。临床观察结果显示,两组治疗后症状较治疗前均明显好转(P<0.05),并且观察组改善显著。观察组胸部X线变化改善率明显优于对照组(P<0.05)。治疗前后体重,观察组患者的体重增加稳定率明显高于对照组,两组比较有显著性意义(P<0.05)。治疗前后Karnofsky评分,观察组治疗后评分明显高于对照组,较对照组有显著性意义(P<0.05)。观察组症状缓解时间及激素使用时间均明显短于对照组,两组比较有显著性意义(P<0.05)。结论:养阴生津方治疗非小细胞肺癌放疗后急性肺损伤可明显提高疗效,改善症状,改善胸部X线表现,稳定体重及提高生活质量,缩短治疗时间,减少激素使用时间等,临床疗效较好,且无毒副作用。Objective.To observe the effect of Yangyin Shengjin Fang （prescription for replenishing yin and producing body fluid） for non small cell lung cancer with acute pneumonia after radiation. Methods：The 60 patients selected according to the enrolment criteria were randomized into the observed group （routine treatment of western medicine 4- Yangyin Shengjin Fang） and the control group （routine treatment of western medicine） with 30 in each. The therapeutic effect,changes of symptoms,findings in X ray,scores of Karnofsky,symptomatic relief,and use of hormone in two groups were observed. Results.The total effective rate of observed group was 90.00 % and of control group 60.00 %. The symptoms of two groups, especially the observed group,were improved greatly after treatment （ P〈0.05）. In the observed group, the improvement of findings in X ray was much better than that of control group （P〈0.05）. The body weight increase of observed group was more obvious than that of control group, the difference was signifi- cant （P〈0.05）. After treatment,the score of Karnofsky of observed group was more obvious than that of control group,the difference was significant （P〈0.05）. The time of symptomatic relief and use of hormone of observed group was obviously shorter than that of control group, the difference was significant （P〈0.05）. Conclusion：Yangyin Shengjin Fang can remarkably enhance the therapeutic effect in the treatment of non small cell lung cancer with acute pneumonia after radiation in relieving symptoms, reducing abnormal findings of X ray, increasing body weight,shortening the treatment duration and use of hormone without any side effect.

关 键 词：非小细胞肺癌 急性放射性肺炎 中医药治疗 

分 类 号：R734.2[医药卫生—肿瘤]