替硝唑在牙周炎治疗中的临床及微生物学观察  

EVALUATION OF THE EFFECT OF TINIDAZOLE ON PERIODONTITIS CLINICAL AND MICROBIOLOGICAL OBSERVATION

作　　者：李耀华[1] 袁诗芬[1] 史蓓菊 

机构地区：[1]上海铁道大学口腔医学院

出　　处：《中国微生态学杂志》1997年第3期18-19,共2页Chinese Journal of Microecology

摘　　要：本文通过对３０例牙周炎患者在口服替硝唑前后的临床症状及龈下菌斑的暗视野显微镜下螺旋体等菌种比例的变化，观察该药对牙周炎及其致病菌的疗效。结果：服用替硝唑后，在龈下菌斑中螺旋体的比例明显下降，而球菌的比例明显增高。牙龈指数、牙龈出血指数和探针深度均较服药前有明显好转（Ｐ＜０．００１）。提示：替硝唑能有效地抑制和杀灭龈下菌斑中的厌氧菌，并迅速消除牙周炎症，减轻症状。Li Yaohua Yuan Shifen Shi Beiju Hospital and Faculty of Stomatology, Shanghai Tie - dao University, Shang hai 200072 Abstract 30 patients with periodontitis were selected and the changes of clinical phenomena and ratio of different bacteria in Darkground microscopy of subgingival plaque before and after trest- ment were compared. The result showed GI. SBI. and PD. as well as the percentagy of spirochaeta decreased obviously but coccus percentages increased relatively after oral intaking of Tinidazole. The result suggested Tinidazole has notable inflammation of periodontal tissue and relieve the clin- ical phenomena rapidly.

关 键 词：替硝唑 牙周炎 临床观察 微生态学 

分 类 号：R783.420.5[医药卫生—口腔医学] R978[医药卫生—临床医学]