528例情感性精神障碍患者临床治疗分析  

Analysis of Drug Use in 528 Patients with Affective Disorder

作　　者：刘玉卿[1] 朱凤英[1] 杨毓章[2] 王仁健[1] 陈春梅[1] 

机构地区：[1]内蒙古精神卫生中心,010010 [2]内蒙古医学院药理教研室,010059

出　　处：《药物流行病学杂志》1997年第3期158-161,共4页Chinese Journal of Pharmacoepidemiology

摘　　要：对528例情感性精神障碍住院患者的用药进行回顾性分析,单一用药者135例,用药10种;联合用药三种方案,其中二药联用357例,三药联用34例,四药联用2例,三种方案共用药15种.抗躁狂相药物使用频度顺序前五位为:碳酸锂、氯氮平、氯丙嗪、氟哌啶醇及卡马西平;抗抑郁相的用药频度顺序为:阿米替林、氯氮平、舒必利、氯丙咪嗪、多虑平.疗效比较,单一用药和二药联用无差异(P>0.05),总有效率皆达100%.A retrospective analysis of drug usage was conducted in 528 hospitalized patients with affective disorder. 135 patients received single drug therapy involving 10 drugs. 357 patients were given two drugs; 34 patients received 3 drugs and 2 patients were treated with 4 drugs. The combination use included 15 drugs. The usage frequencies of top 5 antimaniac drugs were Lithium carbonate, clozapine, chlorpro-mazine, holoperadol and carmazipine. The most frequently used anti-depressants included amitriptyline, clozapine, sulpiride, chlorpromazine and doxepine. No difference in therapeutic effects was found between single drug use and two drug combination use (P>0.05). The total effective rates of both therapies were 100%.

关 键 词：情感性精神障碍 治疗 

分 类 号：R749.405[医药卫生—神经病学与精神病学]