血清药理学方法研究广西藤茶提取物对乙肝病毒的作用  

The Effect of APS of Ampelopsis Grossedentata on Anti-HBV

作　　者：欧贤红[1] 袁叶飞[2] 韦汉燕[1] 罗朝晖[1] 白先群[1] 唐爱莲[1] 冯冬梅[1] 林启云[3] 

机构地区：[1]桂林医学院,541004 [2]泸州医学院,646000 [3]广西中医学院,530021

出　　处：《华夏医药》2007年第6期476-477,483,共3页Hua-xia Medicine

摘　　要：目的研究广西藤茶提取物APS在体外对乙肝病毒（HBV）的作用。方法采用血清药理学方法，将APS含药血清作用于2,2．15细胞，收集细胞上清液，用MTT法测定细胞上清液中HBsAg、HBeAg的含量。结果APS含药血清对2．2．15细胞分泌的HBsAg、HBeAg有显着抑制作用。结论APS对2．2．15细胞分泌乙型肝炎病毒抗原有抑制作用。Objective To investigate the anti-HBV effect of APS. Methods Using MTT assay to investigate the inhibitions of APS mice -serum on 2.2.15 cells expressing HBsAg and HBeAg. Lamivudine was used as the positive control drug. Results The inhibition rate of APS mice-serum on 2.2.15 cells expressing HBsAg and HBeAg was , significant difference. Conclusion APS mice-serum can inhibit the HBsAg and HBeAg expression of 2.2.15 cells.

关 键 词：藤茶APS 2.2.15细胞 抗乙型肝炎病毒 

分 类 号：R575.1[医药卫生—消化系统]