规则性肝切除术治疗原发性肝癌的分析  

Clinical study of anatomical liver resection for hepatocellular carcinoma

作　　者：朱新华[1] 仇毓东[1] 吴亚夫[1] 周建新[1] 徐庆祥[1] 丁义涛[1] 

机构地区：[1]南京大学医学院附属鼓楼医院肝胆外科,江苏省南京市210008

出　　处：《世界华人消化杂志》2007年第31期3305-3309,共5页World Chinese Journal of Digestology

摘　　要：目的:随机对照观察规则性肝切除术治疗原发性肝癌的安全性以及临床疗效,探讨治疗肝癌合理的手术方式.方法:将38例肝切除术治疗原发性肝癌的患者随机分为2组:规则性肝切除术15例.非规则性肝切除术23例,对两组病例的手术和随访情况进行分析评价.结果:两组均无手术死亡,术中出血、并发症发生率、住院时间无显著差异.规则性肝切除标本切缘满意率(大于2cm)较高,术后近期复发率显著降低,一年无瘤生存率高于非规则性肝切除.结论:规则性肝切除是治疗原发性肝癌安全有效的术式,对有适应证的病例应尽可能采用此种手术方式,有望获得较好的疗效.AIM： To evaluate the therapeutic efficacy and safety of anatomical liver resection for hepato- cellular carcinoma （HCC）.METHODS： Thirty-eight patients who under- went liver resection for HCC were randomly divided into two groups： anatomical liver resec- tion group （n = 15） and non-anatomical liver resection group （n = 23）. The amount of intra- operative bleeding and blood transfusion, time of operation, postoperative complications, liver function recovery, recurrence and survival rate were compared between the two groups.RESULTS： No operative death was found in this study, and there was no significant difference in the amount of intraoperative bleeding, postop- erative complication and hospital-stay between the two groups. The rate of satisfactory resec- tion margin （〉 2 cm） was higher in anatomical resection group, and the recurrent rate during one year was decreased significantly. Anatomicresection could also elevate the tumor-free one- year survival rate. CONCLUSION： Anatomic liver resection is safe and effective, and it is more suitable to hepato- cellular carcinoma patients with operative indi- cation than nonanatomic resection.

关 键 词：原发性肝癌 规则性肝切除术 治疗 

分 类 号：R735.7[医药卫生—肿瘤]