Effect of Breathwalk on body composition,metabolic and mood state in chronic hepatitis C patients with insulin resistance syndrome  

作　　者：M Vázquez-Vandyck S Roman JL Vázquez L Huacuja G Khalsa R Troyo-Sanromán A Panduro 

机构地区：[1]Molecular Biology in Medicine,Civil Hospital of Guadalajara,Fray Antonio Alcalde,Guadalaiara Jalisco,México Health Sciences University Center,University of Guadalajara,Guadalajara Jalisco,México [2]Epidemiology Department,Regional General Hospital No.110,Mexican Institute of Social Security and Public Health Department,University of Guadalajara,Guadalajara Jalisco,México [3]Chronic Degenerative Diseases Institute,Health Sciences University Center,University of Guadalajara,Guadalajara Jalisco,México [4]Kundalini Research Institute,Beth Israel Deaconess Medical Center,Harvard Medical School,Boston,MA 02215,United States [5]Research Unit,Health Sciences University Center,University of Guadalajara,Guadalajara Jalisco,México

出　　处：《World Journal of Gastroenterology》2007年第46期6213-6218,共6页世界胃肠病学杂志（英文版）

基　　金：Grant Salud-Conacyt-2004-C01-025 to AP

摘　　要：AIM： To identify the anthropometric, metabolic and mood state in hepatitis C virus （HCV）-infected patients from the west of Mexico and to evaluate the effect of 13reathwalk （13W）, a combination of walking, synchronized breathing and focussed attention, on those patients. METHODS： In an experimental study, 17 patients with serological and molecular diagnosis of HCV, not receiving pharmacological treatment, were studied. One hour sessions of 13W were practiced 3 times at week for six months. Body composition was assessed by electric impedance. Biochemical profiles and insulin resistance （IR） risk was assessed by conventional methods. Mood state was evaluated with specific and open questions at the beginning and at the end of the program. RESULTS： Seventy percent of patients were overweight or obese, and 77% of the patients presented with IR at the beginning of the study. Improvements were observed at the 3^rd mo, and statistically significant differences were recorded at the 6^th mo using the fitness score （76 vs 83, P 〈 0.01）, in alanine aminotransferase （ALT）（106±93 U/L vs 59 ± 32 U/L, P 〈 0.01）, total bilirubin （0.09 ± 1 mg/dL vs 0.62 ± 0.2 mg/dL, P 〈 0.01）, ALT/ AST ratio （1.04 vs 0.70, P 〈 0.01）, triglycerides （165 ± 86 mg/dL vs 124 ± 49 mg/dL, P 〈 0.01） and the IR risk （4.0 vs 2.7）. Most patients （88%） indicated to feel better at the end of BW （P 〈 0.01）.CONCLUSION： Breathwalk has an important effect on body composition, lipid profile and liver enzymes. It is also easy, inexpensive and has a beneficial effect on metabolic and mood state in HCV patients.瞄准：识别人体测量，新陈代谢并且在丙肝病毒(HCV ) 的心情状态从墨西哥并且到的西方感染了病人评估效果 Breathwalk (BW ) ，走的联合，同步 breathing 和集中的注意，在那些病人上。方法：在试验性的研究，有 HCV 的血清学、分子的诊断的 17 个病人，不接受药理学治疗，被学习。BW 的一个小时会议在星期被练习 3 次六个月。身体作文被电的阻抗估计。生物化学的侧面和抗胰岛素性(红外) 冒的风险被常规方法估计。心情状态在开始并且在节目的结束与特定、待研究的问题被评估。结果：百分之七十个病人超重或肥胖，并且 77% 病人在学习的开始与红外介绍了。改进在第三瞬间被观察，并且统计上，有效差量用健康分数在 第6 瞬间被记录( 76 对 83 ， P < 0.01 )，在丙氨酸 aminotransferase (中高音)( 106 +/- 93 U/L 对 59 +/- 32 U/L ， P < 0.01 )，全部的胆红素( 0.09 +/- 1 mg/dL 对 0.62 +/- 0.2 mg/dL ， P < 0.01 )，中高音/著名计算机生产厂商比率( 1.04 对 0.70 ， P < 0.01 )， triglycerides ( 165 +/- 86 mg/dL 对 124 +/- 49 mg/dL ， P < 0.01 )并且 IR 风险( 4.0 对 2.7 )。大多数病人(88%) 显示了感觉到擅长 BW 的结束(P < 0.01 ) 。结论：Breathwalk 在身体作文，类脂化合物侧面和肝酶上有重要效果。它也是容易的，便宜并且穿上有益的效果新陈代谢并且在 HCV 病人的心情状态。

关 键 词：Breathwalk Chronic hepatitis C INSULINRESISTANCE OBESITY Quality of life 

分 类 号：R512.63[医药卫生—内科学]