儿童混合性焦虑抑郁障碍微量生物电脑导入刺激治疗结果  

Results of cranial electrotherapy stimulation to children with mixed anxiety and depressive disorder

作　　者：陈一心[1] 虞琳[1] 张久平[1] 李乐加[1] 陈图农[1] 陈怡[1] 

机构地区：[1]南京医科大学附属脑科医院,210029

出　　处：《上海精神医学》2007年第4期203-205,232,共4页Shanghai Archives of Psychiatry

基　　金：南京市医学科技发展项目(YKK0455)

摘　　要：目的分析儿童混合性焦虑抑郁障碍微量生物电脑导入刺激（Cranial electrotherapy stimulation简称CES）治疗结果。方法将经宗氏抑郁自评量表（SDS）和宗氏焦虑自评量表（SAS）评分均大于40分,符合ICD-10混合性焦虑抑郁障碍的特点的门诊8-16岁初诊儿童30例作为实验组,予CES治疗;将南京市中小学老师推荐的,以同样方法筛选的30例儿童作为对照组,予象征性地CES治疗,2组儿童均接受3个疗程的规范化治疗,3个疗程结束时复查SAS和SDS量表,比较3组疗效、副反应,同时比较治疗前后脑电地形图变化。结果SDS总分：治疗前实验组49.60±7.03,对照组47.23±5.86。SAS：治疗后实验组34.08±7.79,对照组46.83±10.35。SAS总分：治疗前实验组48.27±7.01,对照组46.03±6.24;治疗后实验组29.67±6.03,对照1组39.17±12.73。方差分析显示实验组有明显效果。实验组枕区α1、α2有明显改变。结论CES治疗儿童混合性焦虑抑郁障碍安全有效,脑电地形图枕区α频带功率值有变化。Objective： To analyze the effectiveness of cranial eleetrotherapy stimulation （CES） on children with mixed anxiety and depressive disorder（MAD）. Methods： There are two groups participating in the research, each of which included 30 subjects at the age of 8 to 16 who met MAD criteria of ICD - 10 and whose SDS and SAS scores were more than 40. The experimental group was treated with CES, and the control group was treated with pseudo - CES. Comparison of SDS,SAS and the αwave of occipital lobe between before and after treatment was taken among the two groups. Results： On SDS, there are 49. 60 ± 7. 03 in the experimental group and 47.23 ± 5.86 in the control group before the treatment, but there are 34.08 ± 7.79 in the experimental group and 46.83 ± 10.35 in the control group on SDS after the treatment. On SAS, there are 48.27 ±7.01 in the experimental group and 46.03 ±6. 24 in the control group before the treatment, but there are 29.67 ± 6.03 in the experimental group and 39.17 ± 12.73 in the control group on SDS after the treatment. AVONA indicated that the treatment was significantly effective. The α1 and α2 of occipital lobe improved more in the experimental group. Conclusion：CES is effective for treating Children with MAD. CES can affect brain electricity area mapping of occipital lobe.

关 键 词：微量生物电脑导入刺激 儿童 混合性焦虑抑郁障碍 脑电地形图 

分 类 号：R749.7[医药卫生—神经病学与精神病学]