微波固化对肝癌病人肝功能的影响  

The clinical effects evaluation and the effect of liver function microwave coagulation in the treatment of hepatocelluar carcinoma

作　　者：张丹[1] 秦玉刚[1] 王辉[1] 杨冬艳[1] 王春艳[2] 何尔斯泰[1] 张学文[1] 

机构地区：[1]吉林大学中日联谊医院,吉林长春130033 [2]吉林大学第一临床学院干部病房

出　　处：《中国实验诊断学》2007年第12期1638-1640,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨微波固化对肝癌病人肝功能影响及临床应用价值。方法我院自2004年3月至2007年5月对15例肝癌患者行MTC-3(C)型冷基循环微波聚能手术系统在超声引导下经皮或开腹手术时对肿瘤行微波固化。经过1-39个月[平均8.9月±8.3月]随访,比较术前、术后肝功能变化,探讨应用价值。结果肝癌病人行微波固化后ALT有不同程度升高,但P>0.05。CHE(胆碱酯酶)有不同程度下降,其中多发肝癌患者术后3、7天CHE下降明显,P<0.05。所有病例均完全消融,1例术后1月发生肝内转移。无远处转移。所有随访患者无死亡。结论微波固化对肝癌病人肝功能影响不大,术后并发症少,能获得很好的疗效,尤其是直径小于3 cm的肝癌。Objeelive To study the changes of liver function and the clinical value of microwave coagulation therapy （MCT） in patients of hepatocellular carcinoma. Methods 15 hepatocellular carcinoma patients in the liver were collected and summarized in China-Japan Union Hospital from March 2004 to May 2007. All patients were treated by one or more shot microwave coagulation by Microwave Focused Hyperthermia System under the gnidance of B - type ultrasound . All patients were followed - up 1 to 3 9 months [ mean time：8.9 ± 8.3 months ], the changes of liver function, the clinical value was analyed. Results After MCT, serum ALT increase various levels, but P 〉 0.05, they have no statistieaUy significant difference. While serum CHE decrease after operation and serum CHE has significantly changes （ P 〈 0.05） in 3rd and 7th days after operation in patients with many nodules in the live,they have statistically significant difference. Complete ablation is 100% during CT examination; 1 patient recurs in one month;All of them are notdistant recurrence. All patients are survival and the patient＇s life quality is good. Conclusion There were many advantages to liver cancer using microwave coagulation,such as curative effect,minor damage to liver function,few eomplication,ete.And it has well clinical value and distant survival, especially for those nodules less than 3.0cm in diameter.

关 键 词：肝癌 微波固化 超声引导 

分 类 号：R735.7[医药卫生—肿瘤]