ZT胶栓塞兔门静脉的可行性研究  

Study on feasibility of ZT glue embolization for portal vein in rabbits

作　　者：庄树彤[1] 陈斌[1] 程书榜[1] 倪勇[1] 周汝明[2] 高海斌[1] 王成友[1] 

机构地区：[1]深圳市第二人民医院普外科,518035 [2]深圳市第二人民医院放射科,518035

出　　处：《岭南现代临床外科》2007年第6期403-406,共4页Lingnan Modern Clinics in Surgery

基　　金：深圳市卫生局科技资助项目(200104093)

摘　　要：目的探讨不同浓度ZT胶栓塞兔门静脉的可行性及其机制。方法24只新西兰白兔分为三组,A组、B组分别为ZT胶:碘油1∶1、1∶2混合物组,对照组C组为碘油组,数字减影血管造影(DSA)下对门静脉左支进行栓塞,术后检测门静脉压力、丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)的变化,术后30dDSA下门静脉造影。结果门静脉栓塞(PVE)后门静脉压力、ALT、AST呈一过性升高。术后5min门静脉造影,A组表现为门静脉大分支栓塞,B组、C组为周围性栓塞。术后30d门静脉造影,A组、B组呈永久性栓塞。结论不同浓度ZT胶可选择性栓塞到门静脉各级分支,并造成永久性栓塞。Objective To investigate the feasibility and mechanism of embolization of the portal vein with different concentration of ZT glue in rabbits. Methods Twenty-four white New Zealand rabbits were randomly divided into 3 groups：group A, ZT glue-lipiodol 1 ： 1 mixture, group B, ZT glue-lipiodol 1 ： 2 mixture, group C （control group ） .Portal vein embolization （PVE） of left branch was performed in each group under digital subtraction angiography （DSA）. Portal venous pressure, ALT and AST were measured before and after PVE. Portal phlebography was made by DSA at 30th day after PVE. Results There were transient elevation in portal venous pressure, ALT and AST.The main branches of the portal vein were embolized in group A. Peripheral embolization were found in group B and group C 5 minutes after portal phlebography.There were permanent embolization in Group A and group B at 30th day after PVE. Conclusion The different concentration of ZT glue can selectively embolize the different brances of portal vein and form permanent embolization.

关 键 词：ZT胶 门静脉 栓塞 可行性 

分 类 号：R-332[医药卫生]