十二指肠Brunner腺腺瘤临床病理特点(附病例报告)  

Duodenal Brunner’s gland adenoma: a clinicopathologic study of 4 cases

作　　者：李涌[1] 马乃绪[2] 关慧娟 全刚[1] 刘波[1] 

机构地区：[1]兖州市人民医院 [2]91医院,山东兖州272100 [3]兖州矿务局中心医院,山东兖州272100

出　　处：《实用医药杂志》2007年第12期1423-1425,共3页Practical Journal of Medicine & Pharmacy

摘　　要：目的观察十二指肠Brunner腺腺瘤的临床与病理特点。方法对4例十二指肠Brunner腺腺瘤进行组织形态学观察,并结合文献对其临床与病理特点进行分析。结果患者年龄38～56岁,平均50.4岁,病程2～24个月,4例均有上腹部疼痛史,其中1例伴发溃疡。组织学上以形态正常的十二指肠Brunner腺的结节性增生为特征,伴有散在的导管和间质成分。结论十二指肠Brunner腺腺瘤是一种罕见的良性肿瘤,更可能是一种错构瘤而非真性肿瘤。临床表现缺乏特异性,组织学检查是最可靠的方法。Objective To study the clinicopathologic features of the duodenal Brunner＇s gland adenoma. Methods Four cases of duodenal Brunner＇s gland adenoma were observed with HE. The clinical,histologic features and their follow-up data were also reviewed. Results The age of patients were 38 to 56yr （mean 50.4yr） and all of the patients were first seen with pain of upper belly （layed for 2 months to 2 years）, including associated with duodenal ulcer in 1 patient. Nodular haperplasia of normal glands was the prominent histologic features of Brunner＇s gland adenoma. Conclusions Brunner＇s gland adenoma is a rare benign tumor, it is probably a hamartoma but not a substantial tumor. The patients with Brunner＇s gland adenoma usually do not show characteristic clinical manifestations. Pathological examination is the most reliable methods for the diagnosis.

关 键 词：十二指肠 BRUNNER腺腺瘤 诊断 活组织检查 

分 类 号：R735.31[医药卫生—肿瘤]