黛力新治疗脑卒中后抑郁的临床观察  

Clinical observation of therapeutic effects of Dailixin on depression in patient with stroke

作　　者：武士云[1] 朱继来 宋卫东[3] 

机构地区：[1]安徽省淮南市第二人民医院内科,安徽淮南232072 [2]安徽省安庆市纺织医院内科 [3]安徽省宿州市市立医院神经内科

出　　处：《心血管康复医学杂志》2007年第6期568-570,共3页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：目的:观察黛力新对脑卒中后抑郁及神经功能康复的影响。方法:60例脑卒中患者随机被分为治疗组和对照组,在治疗前和治疗6周后分别评定Hamilton抑郁量表(HAMD)和临床神经功能缺损评分(CNS)。结果:治疗组:HAMD:治疗后(13.03±5.07)显著低于治疗前(23.73±5.70)(P<0.01)及对照组(22.23±2.71)(P<0.01)。两组抑郁疗效有显著差异(P<0.01)。治疗组神经功能缺损评分:治疗后为(9.90±7.23)分,显著低于治疗前的(22.70±7.70)分,P<0.01,及对照组(16.50±6.80)分,P<0.01。两组神经功能康复疗效经Ridit比较有显著性差异(P<0.01)。结论:黛力新可明显改善脑卒中后抑郁程度,并能促进神经功能康复。Objective： To observe the effect of Dailixin on depression in patients with stroke. Methods： Sixty patients with stroke were randomly divided into two groups： therapy group （treated with Dailixin above the base of routine therapy） and control group （treated with routine therapy） and tested with HAMD and clinical neurologic impairment score （CNS） before treatment and six weeks after treatment. Results： The HAMD scores of therapy group were significantly lower （13. 03±5. 07） after treatment than that of before （23.72 ± 5.70）, P〈0. 01, and that of control group （22. 23 ±2. 71）, P〈0. 01. The CNS scores of therapy group were significantly lower （9. 90±7. 23） after treatment than that of before （22. 70±7. 70）, P〈 0. 01, and that of control group （16. 50±6.80）, P〈0. 01. Conclusion： It was indicated that Dailixin can reduce the degree of depression and promote the neurological functional rehabilitation after stroke.

关 键 词：黛力新 脑血管意外 抑郁 

分 类 号：R743.3[医药卫生—神经病学与精神病学]