基于灰色理论的中空海藻酸钠微胶囊释药模型研究  

Research on Release Model of Intra-hollow Sodium Alginate Microcapsules Based on Grey Theory

作　　者：王贤明[1] 吴跃进[1] 余增亮[1] 

机构地区：[1]中国科学院离子束生物工程学重点实验室,合肥230031

出　　处：《材料导报》2007年第12期124-126,共3页Materials Reports

基　　金：中科院方向性项目(KSCXZ-SW-324)

摘　　要：以阿维菌素(AVM)为模型药物,制备了一种中空海藻酸钠(SA)微胶囊。应用灰色系统理论GM(1,1)模型对中空SA微胶囊的缓释性能进行了模拟预测。模型的模拟预测值与实验数据的相对误差较小,表明灰色系统理论可用于模拟和预测中空SA微胶囊的药物释放行为。A kind of intra-hollow microcapsules based on sodium alginate （SA）, avermectin（AVM） is prepared GM（1,1） models for controlled-realse are established by applying the theoretical principles of grey system theory. These models are used to simulate and predict the controlled release behavior. The simulation value and predicting value match the factual value very well. It is showed that the grey system theory can be used to simulate and predict the controlled release behavior.

关 键 词：灰色理论 灰色模型 海藻酸钠 微胶囊 缓释 

分 类 号：TQ314.1[化学工程—高聚物工业]